(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Base Information

Chemical Name:(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane
CAS No.:1443542-46-8
Molecular Formula:C₂₆H₃₈O₅Si
Molecular Weight:458.67
Hs Code.:

Synonyms:(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Suppliers and Price of (Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

There total 9 articles about (Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1443542-45-7
(2,4-bis(4-(methoxymethoxy)phenyl)but-3-ynyloxy)(tert-butyl)dimethylsilane

: 1443542-46-8
(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Guidance literature:: With quinoline; 10% Pd-CaCO3; hydrogen; In ethyl acetate; for 2h;
DOI:10.5012/bkcs.2013.34.4.1247

Reference yield:

: 540-38-5
p-Iodophenol

: 1443542-46-8
(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Guidance literature:: Multi-step reaction with 6 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine / toluene / 24 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / 20 °C / Inert atmosphere; Cooling with ice

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -50 - 0 °C / Inert atmosphere

4.2: 1 h

4.3: 0.5 h / -20 °C

5.1: 1H-imidazole / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

5.2: 1 h / 20 °C

6.1: hydrogen; 10% Pd-CaCO3; quinoline / ethyl acetate / 2 h

With 1H-imidazole; quinoline; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; n-butyllithium; 10% Pd-CaCO3; tetrabutyl ammonium fluoride; hydrogen; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; dichloromethane; ethyl acetate; toluene; 1.1: |Sonogashira Cross-Coupling;
DOI:10.5012/bkcs.2013.34.4.1247

Reference yield:

: 220882-37-1
4-(methoxymethoxy)-1-ethynylbenzene

: 1443542-46-8
(Z)-(2,4-bis(4-(methoxymethoxy)phenyl)but-3-enyloxy)(tert-butyl)dimethylsilane

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -50 - 0 °C / Inert atmosphere

1.2: 1 h

1.3: 0.5 h / -20 °C

2.1: 1H-imidazole / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

2.2: 1 h / 20 °C

3.1: hydrogen; 10% Pd-CaCO3; quinoline / ethyl acetate / 2 h

With 1H-imidazole; quinoline; n-butyllithium; 10% Pd-CaCO3; hydrogen; In tetrahydrofuran; hexane; dichloromethane; ethyl acetate;
DOI:10.5012/bkcs.2013.34.4.1247