C₃₉H₄₉N₅O₁₁

Base Information

• Chemical Name: C₃₉H₄₉N₅O₁₁
• CAS No.: 1404363-71-8
• Molecular Formula: C₃₉H₄₉N₅O₁₁
• Molecular Weight: 763.845
• Mol file: 1404363-71-8.mol

Synonyms:C₃₉H₄₉N₅O₁₁

Chemical Property of C₃₉H₄₉N₅O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₄₉N₅O₁₁

There total 4 articles about C₃₉H₄₉N₅O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + α-BOC-di-ε-Z-lysyllysine (27317-71-1) → C39H49N5O11 (1404363-71-8)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at -10 - 20 ℃; Inert atmosphere;

DOI:10.1002/pola.26208

Reference yield:

methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride (27894-50-4) → C39H49N5O11 (1404363-71-8)

Guidance literature:

Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 12.5 h / -15 - 20 °C / Inert atmosphere

2: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 7 h / 0 - 20 °C / Inert atmosphere

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / -10 - 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/pola.26208

Reference yield:

Boc-Lys(Z)-OSu (34404-36-9) → C39H49N5O11 (1404363-71-8)

Guidance literature:

Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 12.5 h / -15 - 20 °C / Inert atmosphere

2: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 7 h / 0 - 20 °C / Inert atmosphere

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / -10 - 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/pola.26208

upstream raw materials:

methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride

4-nitro-phenol

α-BOC-di-ε-Z-lysyllysine

Boc-Lys(Z)-OSu

Downstream raw materials:

α-BOC-tetra-ε-Z-lys₄OH

C₆₇H₈₅N₉O₁₇

C₆₂H₈₄N₈O₁₅