Benzyl 3-aminopyrrolidine-1-carboxylate

Base Information

Chemical Name:Benzyl 3-aminopyrrolidine-1-carboxylate
CAS No.:185057-50-5
Molecular Formula:C12H16N2O2
Molecular Weight:220.271
Hs Code.:2933990090
European Community (EC) Number:672-228-4
DSSTox Substance ID:DTXSID20939924
Mol file:185057-50-5.mol

Synonyms:Benzyl 3-aminopyrrolidine-1-carboxylate;185057-50-5;3-amino-1-n-cbz-pyrrolidine;1-cbz-3-aminopyrrolidine;n-cbz-3-aminopyrrolidine;3-amino-pyrrolidine-1-carboxylic acid benzyl ester;MFCD03001673;(S)-(-)-1-Cbz-3-aminopyrrolidine;1004538-28-6;1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-, PHENYLMETHYL ESTER;1-cbz-3-amino pyrrolidine;1-n-cbz-3-aminopyrrolidine;(R)-1-Cbz-3-aminopyrrolidine;1-benzyloxycarbonyl-3-aminopyrrolidine;3-amino cbz-pyrrolidine;1-Cbz-3-amino-pyrrolidine;SCHEMBL266047;(R)-1-Cbz-3-amino-pyrrolidine;(S)-1-Cbz-3-amino-pyrrolidine;DTXSID20939924;FPXJNSKAXZNWMQ-UHFFFAOYSA-N;BCP29000;AKOS015855108;PB29222;PB29412;PB34104;SB10254;SB10255;benzyl-3-amino-1-pyrrolidinecarboxylate;DS-14366;SY004621;SY238536;A4098;FT-0603860;FT-0603861;FT-0643764;FT-0654590;EN300-1723116;A800209;benzyl 3-aminopyrrolidine-1-carboxylate, AldrichCPR;Q-102158;3-amino-1-pyrrolidinecarboxylic acid (phenylmethyl) ester;Benzyl (3R)-3-aminopyrrolidine-1-carboxylate;(3R)-1-N-Cbz-3-Aminopyrrolidine

Suppliers and Price of Benzyl 3-aminopyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzyl3-Aminopyrrolidine-1-carboxylate
100mg
$ 75.00

Synthonix
3-Amino-1-Cbz-pyrrolidine 95+%
1g
$ 50.00

Matrix Scientific
Benzyl 3-Aminopyrrolidine-1-carboxylate 97%
1g
$ 249.00

J&W Pharmlab
3-Amino-pyrrolidine-1-carboxylicacidbenzylester 98%
5g
$ 124.00

J&W Pharmlab
3-Amino-pyrrolidine-1-carboxylicacidbenzylester 98%
25g
$ 495.00

Crysdot
Benzyl3-aminopyrrolidine-1-carboxylate 95+%
25g
$ 554.00

Crysdot
Benzyl3-aminopyrrolidine-1-carboxylate 95+%
1g
$ 35.00

Crysdot
Benzyl3-aminopyrrolidine-1-carboxylate 95+%
10g
$ 257.00

Crysdot
Benzyl3-aminopyrrolidine-1-carboxylate 95+%
5g
$ 139.00

Chemenu
Benzyl3-Aminopyrrolidine-1-carboxylate 95%
10g
$ 243.00

Total 52 raw suppliers

Chemical Property of Benzyl 3-aminopyrrolidine-1-carboxylate

Chemical Property:

Vapor Pressure:4.04E-05mmHg at 25°C
Refractive Index:1.571
Boiling Point:351.7 °C at 760 mmHg
PKA:9.52±0.20(Predicted)
Flash Point:166.5 °C
PSA：55.56000
Density:1.186 g/cm³
LogP:1.99440
Sensitive.:Air Sensitive
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:239

Purity/Quality:

99% ^*data from raw suppliers

Benzyl3-Aminopyrrolidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC1N)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 3-aminopyrrolidine-1-carboxylate

There total 5 articles about Benzyl 3-aminopyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 68471-57-8
2,3-dihydro-pyrrole-1-carboxylic acid benzyl ester

: 185057-50-5
(S)-3-Amino-1-pyrrolidinecarboxylic acid,phenylmethyl ester

Guidance literature:: With iridium(lll) bis[2-(2,4-difluorophenyl)-5-methylpyridine-N,C₂₀]-4,40-di-tert-butyl-2,20-bipyridine hexafluorophosphate; 2,4,6-Triisopropylthiophenol; ammonia; In methanol; toluene; at 20 ℃; for 16h; Solvent; regioselective reaction; Inert atmosphere; Irradiation;
DOI:10.1002/chem.202003562