1-BOC-5-methoxyindole

Base Information

Chemical Name:1-BOC-5-methoxyindole
CAS No.:99275-47-5
Molecular Formula:C14H17NO3
Molecular Weight:247.294
Hs Code.:2933990090
European Community (EC) Number:624-821-4
DSSTox Substance ID:DTXSID00474161
Nikkaji Number:J416.466K
Wikidata:Q72449867
Mol file:99275-47-5.mol

Synonyms:99275-47-5;1-BOC-5-methoxyindole;N-Boc-5-methoxyindole;tert-butyl 5-methoxy-1H-indole-1-carboxylate;Tert-butyl 5-methoxyindole-1-carboxylate;1H-Indole-1-carboxylic acid, 5-methoxy-, 1,1-dimethylethyl ester;MFCD08272248;1-Boc-5-methoxy-1H-indole;N-Boc-5-methoxyindole, 97%;SCHEMBL2266733;DTXSID00474161;LPSLGTZFBDZNEK-UHFFFAOYSA-N;ZDA27547;AM1238;AKOS005135852;5-Methoxy-1H-indole, N-BOC protected;AC-23421;BS-22422;SY104182;CS-0187679;FT-0642394;tert-butyl5-methoxy-1H-indole-1-carboxylate;A12968;5-Methoxy-indole-1-carboxylic acid tert-butyl ester

Suppliers and Price of 1-BOC-5-methoxyindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N-Boc-5-methoxyindole 97%
10g
$ 310.00

Sigma-Aldrich
N-Boc-5-methoxyindole 97%
1g
$ 54.70

Crysdot
tert-Butyl5-methoxy-1H-indole-1-carboxylate 95+%
5g
$ 145.00

Chemenu
N-Boc-5-Methoxyindole 95%
25g
$ 288.00

American Custom Chemicals Corporation
N-BOC-5-METHOXYINDOLE 95.00%
5G
$ 1076.73

American Custom Chemicals Corporation
N-BOC-5-METHOXYINDOLE 95.00%
1G
$ 664.82

Alichem
tert-Butyl5-methoxy-1H-indole-1-carboxylate
25g
$ 329.56

AK Scientific
N-Boc-5-Methoxyindole
5g
$ 171.00

AHH
N-Boc-5-Methoxyindole 98%
5g
$ 350.00

Total 31 raw suppliers

Chemical Property of 1-BOC-5-methoxyindole

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:82-85 °C
Refractive Index:1.532
Boiling Point:357.34 °C at 760 mmHg
Flash Point:169.913 °C
PSA：40.46000
Density:1.1 g/cm³
LogP:3.43310
Storage Temp.:Keep Cold
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:247.12084340
Heavy Atom Count:18
Complexity:311

Purity/Quality:

97% ^*data from raw suppliers

N-Boc-5-methoxyindole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C=CC2=C1C=CC(=C2)OC
Uses Reactant for preparation of:? ;Asymmetric intramolecular Friedel-Crafts alkylation reaction1? ;Palladium-catalyzed carboaminoxylations with arylboronic acids and TEMPO catalyst2? ;Fluorescent pyrimidopyrimidoindole nucleosides via Suzuki-Miyaura coupling reaction3? ;Novel conformationally restricted β- and γ-amino acids4? ;2-(Indolyl) borates, silanes, and silanols5? ;DNA minor groove alkylating agents as stable amine-based prodrugs designed for tumor-specific release6 Reactant for preparation of:Asymmetric intramolecular Friedel-Crafts alkylation reactionPalladium-catalyzed carboaminoxylations with arylboronic acids and TEMPO catalystFluorescent pyrimidopyrimidoindole nucleosides via Suzuki-Miyaura coupling reactionNovel conformationally restricted β- and γ-amino acids2-(Indolyl) borates, silanes, and silanolsDNA minor groove alkylating agents as stable amine-based prodrugs designed for tumor-specific release

Technology Process of 1-BOC-5-methoxyindole

There total 11 articles about 1-BOC-5-methoxyindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1006-94-6
5-methoxylindole

: 24424-99-5
di-tert-butyl dicarbonate

: 99275-47-5
1-(tert-butyloxycarbonyl)-5-methoxyindole

Guidance literature:: With dmap; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1039/b001685n

Reference yield: 84.0%

: 138344-11-3
2-Hydroxy-5-methoxy-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester

: 99275-47-5
1-(tert-butyloxycarbonyl)-5-methoxyindole

Guidance literature:: With toluene-4-sulfonic acid; In ethanol; for 13h; Ambient temperature;

Reference yield: 59.0%

: 75-07-0,9002-91-9
acetaldehyde

: 192189-10-9
3-iodo-5-methoxyindole-1-carboxylic acid tert-butyl ester

: 1239950-40-3
3-(1-hydroxyethyl)-5-methoxyindole-1-carboxylic acid tert-butyl ester

: 99275-47-5
1-(tert-butyloxycarbonyl)-5-methoxyindole

Guidance literature:: 3-iodo-5-methoxyindole-1-carboxylic acid tert-butyl ester; With TurboGrignard; In tetrahydrofuran; at 0 ℃; for 0.2h;

acetaldehyde; In tetrahydrofuran; at 0 ℃; for 0.116667h;
DOI:10.1002/chem.200903284