Tert-butyl 4-cyclopropylpiperazine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-cyclopropylpiperazine-1-carboxylate
CAS No.:77278-34-3
Molecular Formula:C12H22N2O2
Molecular Weight:226.319
Hs Code.:2933599090
DSSTox Substance ID:DTXSID40604743
Nikkaji Number:J2.854.395F
Wikidata:Q82502765
Mol file:77278-34-3.mol

Synonyms:77278-34-3;TERT-BUTYL 4-CYCLOPROPYLPIPERAZINE-1-CARBOXYLATE;1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER;SCHEMBL63877;N-Boc-N'-cyclopropyl-piperazine;DTXSID40604743;UNCLAXHNVIYBNX-UHFFFAOYSA-N;AMY39705;AKOS011324307;AB10366;MB06613;A839021;TERT-BUTYL4-CYCLOPROPYLPIPERAZINE-1-CARBOXYLATE;1-cyclopropyl-4-(1,1-dimethylethoxycarbonyl)piperazine;4-Cyclopropylpiperazine-1-carboxylic Acid tert-butyl Ester

Suppliers and Price of Tert-butyl 4-cyclopropylpiperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
1G
$ 796.95

American Custom Chemicals Corporation
1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
500MG
$ 704.55

American Custom Chemicals Corporation
1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
100MG
$ 635.25

Total 14 raw suppliers

Chemical Property of Tert-butyl 4-cyclopropylpiperazine-1-carboxylate

Chemical Property:

Boiling Point:296.5 °C at 760 mmHg
Flash Point:133.1 °C
PSA：32.78000
Density:1.116 g/cm³
LogP:1.57730
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:226.168127949
Heavy Atom Count:16
Complexity:261

Purity/Quality:

97% ^*data from raw suppliers

1-CYCLOPROPYLPIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCN(CC1)C2CC2

Technology Process of Tert-butyl 4-cyclopropylpiperazine-1-carboxylate

There total 4 articles about Tert-butyl 4-cyclopropylpiperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 27374-25-0
[(1-Ethoxycyclopropyl)oxy]trimethylsilane

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 77278-34-3
4-cyclopropylpiperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: [(1-Ethoxycyclopropyl)oxy]trimethylsilane; 1-t-Butoxycarbonylpiperazine; With sodium hydroxide; sodium cyanoborohydride; acetic acid; In methanol; at 60 ℃; for 5h;

With water; In methanol; for 0.0833333h;

With sodium hydroxide; In methanol; water; for 0.25h;

Reference yield: 100.0%

: 84098-43-1
trimethylsilyl ether of 1-methoxycyclopropanol

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 77278-34-3
4-cyclopropylpiperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; methanol; at 63 ℃; for 16h;
DOI:10.1021/jm031028z

Reference yield: 97.0%

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 411235-57-9
cyclopropylboronic acid

: 77278-34-3
4-cyclopropylpiperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With [2,2]bipyridinyl; oxygen; copper diacetate; sodium carbonate; In 1,2-dichloro-ethane; at 70 ℃;
DOI:10.1039/b925499d