Technology Process of 5-ferrocene-1,3-benzenedicarboxylic acid
There total 3 articles about 5-ferrocene-1,3-benzenedicarboxylic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
ethanol;
for 16h;
Reflux;
DOI:10.1039/c4dt02591a
- Guidance literature:
-
With
HCl; NaNO2; hexadecantyltrimethylammonium bromide;
In
diethyl ether; water;
concd. HCl was added to aq. soln. of acid; aq. soln. of NaNO2 was slowlyadded with stirring at 0-5°C for 20 min; stand for 30 min; urea was added; added to soln. of Fe complex and bromide (catalyst) in Et2O; reacted at 10°C for 4 h; Et2O removed; soln. of NaOH added to pH 13; filtered; concd. HCl added to pH 2; cooled; recrystd. (MeOH/H2O, 3/2);
DOI:10.1016/j.jorganchem.2008.07.034
- Guidance literature:
-
With
concd. HCl; hexadecanyltrimethylammonium bromide; NaOH;
In
diethyl ether; H2O;
aq. NaNO2 added to aq. 5-aminoisophthalic acid/concd. HCl; stirred for 20 min in ice bath; stood for 30 min; urea added; added to Et2O soln. of ferrocene/hexadecanyltrimethylammonium bromide; stirred for 4 h at 10°C; Et2O removed from mixt.; pH set to 13 with NaOH; filtered off; concd. HCl added until pH 2 reached; pptd. by cooling; recrystd. from MeOH/H2O; detn. by HRMS;
DOI:10.1002/zaac.200900270
