(R)-2-Chloro-1-(pyridin-3-yl)ethanol

Base Information

Chemical Name:(R)-2-Chloro-1-(pyridin-3-yl)ethanol
CAS No.:173901-03-6
Molecular Formula:C₇H₈ClNO
Molecular Weight:157.6
Hs Code.:
DSSTox Substance ID:DTXSID90464652
Wikidata:Q72504660
Mol file:173901-03-6.mol

Synonyms:173901-03-6;(R)-2-Chloro-1-(pyridin-3-yl)ethanol;(R)-1-(Pyrid-3-yl)-2-chloroethanol;(1R)-2-chloro-1-pyridin-3-ylethanol;3-Pyridinemethanol, alpha-(chloromethyl)-, (alphaR)-;(R)-1-(pyrid-3-yl)-2-chloroethan-1-ol;(R)-2-Chloro-1-(3-pyridyl)ethanol;(1R)-2-Chloro-1-(3-pyridyl)ethanol;(1R)-2-Chloro-1-(pyridin-3-yl)ethan-1-ol;SCHEMBL5479042;DTXSID90464652;LCBCRIBFOZSPJL-ZETCQYMHSA-N;(R)-2-chloro-1-pyridin-3-ylethanol;AKOS006279404;AC-25516;(R)-2-chloro-1-pyridin-3-ylethan-1-ol;(R)-alpha-Chloromethyl-3-pyridinemethanol

Suppliers and Price of (R)-2-Chloro-1-(pyridin-3-yl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-Chloro-1-(3-pyridyl)ethanol
250mg
$ 165.00

TRC
(R)-2-Chloro-1-(3-pyridyl)ethanol
2.5g
$ 1320.00

American Custom Chemicals Corporation
(R)-1-(PYRID-3-YL)-2-CHLOROETHAN-1-OL 95.00%
5G
$ 909.56

American Custom Chemicals Corporation
(R)-1-(PYRID-3-YL)-2-CHLOROETHAN-1-OL 95.00%
1G
$ 525.00

Total 14 raw suppliers

Chemical Property of (R)-2-Chloro-1-(pyridin-3-yl)ethanol

Chemical Property:

Vapor Pressure:0.00053mmHg at 25°C
Refractive Index:1.557
Boiling Point:299.5 °C at 760 mmHg
PKA:12.53±0.20(Predicted)
Flash Point:134.9 °C
PSA：33.12000
Density:1.259 g/cm³
LogP:1.35380
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:157.0294416
Heavy Atom Count:10
Complexity:99.6

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Chloro-1-(3-pyridyl)ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)C(CCl)O
Isomeric SMILES:C1=CC(=CN=C1)[C@H](CCl)O
Uses (R)-2-Chloro-1-(3-pyridyl)ethanol is used in the synthetic preparation of chiral amino(pyridinyl)ethanol via lipase-mediated kinetic resolution.

Technology Process of (R)-2-Chloro-1-(pyridin-3-yl)ethanol

There total 8 articles about (R)-2-Chloro-1-(pyridin-3-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 61889-48-3
2-chloro-1-(3-pyridinyl)ethanone hydrochloride

: 173901-03-6
(R)-2-chloro-1-(3-pyridyl)-ethanol

Guidance literature:: With triethylamine; (-)-diisopinocamphenylborane chloride; In tetrahydrofuran; at -25 ℃; for 72h;

Reference yield: 71.0%

: 55484-11-2
2-chloro-1-(pyridin-3-yl)ethan-1-one

: 173901-03-6
(R)-2-chloro-1-(3-pyridyl)-ethanol

Guidance literature:: With formic acid; triethylamine; RuCl[(1R,2R)-p-TsNCH(Ph)-CH(Ph)NH2](η⁶-p-cymene); at 20 ℃; for 0.75h; under 30 Torr;
DOI:10.1016/j.tetasy.2006.07.017

Reference yield: 41.0%

: rac-2-chloro-1-(pyridin-3-yl)ethanol

: 108-05-4,9003-20-7
vinyl acetate

: (S)-3-[(1-acetoxy-2-chloro)ethyl]pyridine

: 515179-33-6
(S)-2-chloro-1-(pyridin-3-yl)ethanol

: 173901-03-6
(R)-2-chloro-1-(3-pyridyl)-ethanol

Guidance literature:: With Candida antarctica SP₄₃₅-L lipase; In hexane; at 37 ℃; for 144h; Further Variations:; Reagents; Product distribution;
DOI:10.1016/j.bmc.2005.09.046