9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Base Information

Chemical Name:9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester
CAS No.:666739-65-7
Molecular Formula:C₂₇H₃₉Cl₃O₈
Molecular Weight:597.961
Hs Code.:

Synonyms:9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Suppliers and Price of 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

There total 3 articles about 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 540-88-5
acetic acid tert-butyl ester

: 637003-51-1
carbonic acid [1-(2-benzyloxy-1-methylethyl)-2,4,4-trimethyl-3,5-dioxopentyl ester] 2,2,2-trichloroethyl ester

: 666739-65-7
9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1002/anie.200352361

Reference yield:

: 503818-15-3
7-benzyloxy-5-hydroxy-1,1-diisopropyl-2,2,4,6-tetramethylheptan-3-one

: 666739-65-7
9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 92 percent / pyridine / CH₂Cl₂ / 1 h / 20 °C

2.1: 76 percent / aq. p-TsOH / tetrahydrofuran / 5 h / 70 °C

3.1: LDA / diethyl ether / 0.5 h / -78 °C

3.2: 80 percent / diethyl ether / 1 h

With pyridine; toluene-4-sulfonic acid; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja046992g

Reference yield:

: 666739-81-7
carbonic acid [1-(2-benzyloxy-1-methylethyl)-5,5-diisopropoxy-2,4,4-trimethyl-3-oxopentyl ester] 2,2,2-trichloroethyl ester

: 666739-65-7
9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: 76 percent / aq. p-TsOH / tetrahydrofuran / 5 h / 70 °C

2.1: LDA / diethyl ether / 0.5 h / -78 °C

2.2: 80 percent / diethyl ether / 1 h

With toluene-4-sulfonic acid; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja046992g