(R)-3-phenyl-3-hydroxypropanal

Base Information

• Chemical Name: (R)-3-phenyl-3-hydroxypropanal
• CAS No.: 133271-00-8
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.177

Synonyms:(R)-3-phenyl-3-hydroxypropanal

Chemical Property of (R)-3-phenyl-3-hydroxypropanal

Chemical Property:

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Technology Process of (R)-3-phenyl-3-hydroxypropanal

There total 8 articles about (R)-3-phenyl-3-hydroxypropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) + acetaldehyde (75-07-0,9002-91-9) → (R)-3-phenyl-3-hydroxypropanal (133271-00-8)

Guidance literature:

With (S)-(-)-α,α-bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol; In N,N-dimethyl-formamide; at 23 ℃; for 72h;

DOI:10.1002/anie.200704870

Reference yield:

C12H10CrO5 → (R)-3-phenyl-3-hydroxypropanal (133271-00-8)

Guidance literature:

With air; In diethyl ether; Irradiation;

DOI:10.1016/j.tet.2018.04.022

Reference yield:

(R,E)-3-(4-hydroxy-4-phenylbut-1-en-1-yl)cyclohex-2-en-1-one (1452591-09-1) → (R)-3-phenyl-3-hydroxypropanal (133271-00-8)

Guidance literature:

With ozone; In methanol; at -78 ℃; Inert atmosphere;

DOI:10.1002/asia.201300997

upstream raw materials:

benzaldehyde

(R)-1-Phenylbut-3-en-1-ol

1-Phenyl-3-buten-1-ol

(+)-(R)-1-phenylbut-3-en-1-yl acetate

Downstream raw materials:

(R)-3-phenyl-3-hydroxypropionic acid

(R)-3-phenyl-1,3-dihydroxypropane

(4R)-4-hydroxy-4-phenylbutan-2-one

(R)-N-methyl-3-phenyl-3-hydroxypropylamine

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