2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

Base Information

Chemical Name:2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide
CAS No.:1311376-60-9
Molecular Formula:C₂₅H₂₄Cl₂N₂O₂
Molecular Weight:455.384
Hs Code.:

Synonyms:2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

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Chemical Property of 2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

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Technology Process of 2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

There total 4 articles about 2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₁₉Cl₂NO₂

: 108-42-9
3-chloro-aniline

: 1311376-60-9
2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

Guidance literature:: With triethylamine; In dichloromethane; at -10 - 20 ℃; for 3h; Inert atmosphere;

Reference yield:

: 61154-45-8
2-(2-oxopropyl)cycloheptan-1-one

: 1311376-60-9
2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 20 °C

2: dichloromethane / -60 - 20 °C / Inert atmosphere

3: triethylamine / dichloromethane / 3 h / -10 - 20 °C / Inert atmosphere

With triethylamine; In dichloromethane;

Reference yield:

: 104-86-9
4-chlorobenzylamine

: 1311376-60-9
2-(1-(4-chlorobenzyl)-2-methyl-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-3-yl)-N-(3-chlorophenyl)-2-oxoacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 20 °C

2: dichloromethane / -60 - 20 °C / Inert atmosphere

3: triethylamine / dichloromethane / 3 h / -10 - 20 °C / Inert atmosphere

With triethylamine; In dichloromethane;