1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea

Base Information

Chemical Name:1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea
CAS No.:107676-55-1
Molecular Formula:C₁₄H₁₃FN₂O₂
Molecular Weight:260.268
Hs Code.:
European Community (EC) Number:666-677-5
NSC Number:158970
Nikkaji Number:J3.500.551J

Synonyms:1-(4-fluorophenyl)-3-(4-methoxyphenyl)urea;NSC158970;Cambridge id 5358745;Oprea1_270287;SCHEMBL4921448;STK979728;AKOS003746299;NSC-158970;N-(4-fluorophenyl)-N'-(4-methoxyphenyl)urea;AB00082863-01;SR-01000206949;SR-01000206949-1

Suppliers and Price of 1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:260.09610582
Heavy Atom Count:19
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)F

Technology Process of 1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea

There total 6 articles about 1-(4-Fluorophenyl)-3-(4-methoxyphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 201230-82-2
carbon monoxide

: 3296-02-4
p-azidofluorobenzene

: 104-94-9
4-methoxy-aniline

: 107676-55-1
3-(4-fluorophenyl)-1-(4-methoxyphenyl)urea

Guidance literature:: With palladium 10% on activated carbon; tetrabutyl-ammonium chloride; XPhos; In water; toluene; at 20 ℃; for 24h; under 760.051 Torr; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.6b00381

Reference yield: 93.0%

: 107676-55-1
3-(4-fluorophenyl)-1-(4-methoxyphenyl)urea

Guidance literature:: With palladium on activated charcoal; XPhos; In toluene; at 60 ℃; for 12h;

Reference yield: 78.0%

: 352-34-1
4-fluoro-1-iodobenzene

: 1566-42-3
p-anisidine urea

: 107676-55-1
3-(4-fluorophenyl)-1-(4-methoxyphenyl)urea

Guidance literature:: With copper(I) oxide; potassium tert-butylate; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 0.333333h; Inert atmosphere; Microwave irradiation;
DOI:10.1016/j.cclet.2010.09.037