N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Base Information

Chemical Name:N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide
CAS No.:1427407-24-6
Molecular Formula:C₁₉H₁₁ClF₃NO₂
Molecular Weight:377.75
Hs Code.:

Synonyms:N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Suppliers and Price of N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

There total 7 articles about N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 1214382-15-6
C₁₃H₇ClF₂O

: 1427407-23-5
3-amino-2-chloro-4-fluoro-phenol

: 1427407-24-6
N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 886499-40-7
2-chloro-6-fluoro-3-methoxy-benzoic acid

: 1427407-24-6
N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C

1.2: 0 - 70 °C

2.1: boron tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: sodium hydrogencarbonate / tetrahydrofuran / 0 - 20 °C

With oxalyl dichloride; boron tribromide; sodium hydrogencarbonate; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1017777-58-0
2-chloro-6-fluoro-3-methoxy-aniline

: 1427407-24-6
N-(2-chloro-6-fluoro-3-hydroxy-phenyl)-2-fluoro-5-(3-fluorophenyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere

2: sodium hydrogencarbonate / tetrahydrofuran / 0 - 20 °C

With boron tribromide; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane;