2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

Base Information

Chemical Name:2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride
CAS No.:699011-27-3
Molecular Formula:C₁₂H₄Cl₃F₄NO₂S
Molecular Weight:408.588
Hs Code.:

Synonyms:2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

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Chemical Property of 2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

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Technology Process of 2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

There total 3 articles about 2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 460986-39-4
3-chloro-2-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)pyridine

: 699011-27-3
2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; at 130 ℃; for 8h;
DOI:10.1021/jf504018z

Reference yield:

: 69045-84-7
2,3-dichloro-5-trifluoromethylpyridine

: 699011-27-3
2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / ClSO₃H / 130 °C

With chlorosulfonic acid; 1: Suzuki coupling;
DOI:10.2533/000942903777678650

Reference yield:

: 160591-91-3
4-chloro-2-fluorophenylboronic acid

: 699011-27-3
2-chloro-5-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-fluorobenzene-1-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / ClSO₃H / 130 °C

With chlorosulfonic acid; 1: Suzuki coupling;
DOI:10.2533/000942903777678650