1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone

Base Information

Chemical Name:1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone
CAS No.:845823-12-3
Molecular Formula:C8H3 F5 O
Molecular Weight:210.103
Hs Code.:29147000
European Community (EC) Number:675-502-1
DSSTox Substance ID:DTXSID90375097
Wikidata:Q72499751
Mol file:845823-12-3.mol

Synonyms:845823-12-3;1-(3,5-difluorophenyl)-2,2,2-trifluoroethanone;2,2,2,3',5'-Pentafluoroacetophenone;1-(3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one;MFCD01319993;2,2,2-trifluoro-3',5'-difluoroacetophenone;2,2,2,3',5'-PENTFLUOROACETOPHENONE;3',5'-Difluoro-2,2,2-trifluoroacetophenone;SCHEMBL3644955;DTXSID90375097;CL8646;2,2,2,3'5'-pentafluoroacetophenone;AKOS012259167;AB08943;DS-2066;SY047596;FT-0646594;A840857;A864070;1-(3,5-difluoro-pehnyl)-2,2,2-trifluoro-ethanone;1-(3,5-difluoro-phenyl)-2,2,2-trifluoro-ethanone;1-[3,5-bis(fluoranyl)phenyl]-2,2,2-tris(fluoranyl)ethanone;2,2,2,3 inverted exclamation mark ,5 inverted exclamation mark -Pentafluoroacetophenone

Suppliers and Price of 1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone
500mg
$ 75.00

SynQuest Laboratories
2,2,2,3',5'-Pentafluoroacetophenone 97%
5 g
$ 64.00

SynQuest Laboratories
2,2,2,3',5'-Pentafluoroacetophenone 97%
25 g
$ 176.00

Rieke Metals
2,2,2,3',5'-Pentafluoroacetophenone 97%
1g
$ 340.00

Rieke Metals
2,2,2,3',5'-Pentafluoroacetophenone 97%
2g
$ 516.00

Matrix Scientific
2,2,2,3',5'-Pentafluoroacetophenone
5g
$ 989.00

Matrix Scientific
2,2,2,3',5'-Pentafluoroacetophenone
1g
$ 359.00

Matrix Scientific
2,2,2,3',5'-Pentafluoroacetophenone
2g
$ 513.00

Crysdot
1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone 97%
100g
$ 446.00

Chemenu
1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone 95%+
100g
$ 421.00

Total 34 raw suppliers

Chemical Property of 1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone

Chemical Property:

Boiling Point:173.4oC at 760 mmHg
Flash Point:62.7oC
PSA：17.07000
Density:1.441g/cm3
LogP:2.70980
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:210.01040553
Heavy Atom Count:14
Complexity:214

Purity/Quality:

97% ^*data from raw suppliers

1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1F)F)C(=O)C(F)(F)F

Technology Process of 1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone

There total 2 articles about 1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 340-07-8
N-(trifluoroacetyl)piperidine

: 461-96-1
3,5-difluorobromobenzene

: 845823-12-3
1-(3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one

Guidance literature:: 3,5-difluorobromobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

N-(trifluoroacetyl)piperidine; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 3h;
DOI:10.1002/anie.201307903

Reference yield:

: 201230-82-2
carbon monoxide

: 2265-91-0
1,3-difluoro-5-iodobenzene

: C₅₅H₄₆CuF₃P₃

: 845823-12-3
1-(3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one

Guidance literature:: With diiodobis(triphenylphosphino)palladium(II); In 5,5-dimethyl-1,3-cyclohexadiene; at 70 ℃; for 24h; under 15001.5 Torr; Autoclave;
DOI:10.1039/c6ra12287f

Reference yield: 85.0%

: 108-24-7
acetic anhydride

: 845823-12-3
1-(3,5-difluorophenyl)-2,2,2-trifluoroethan-1-one

: (Z)-3-(3,5-difluorophenyl)-4,4,4-trifluorobut-2-enoic acid

: 1104077-72-6
(E)-3-(3,5-difluorophenyl)-4,4,4-trifluorobut-2-enoic acid

Guidance literature:: acetic anhydride; 2,2,2,3’,5’-pentafluoroacetophenone; With sodium acetate; at 100 ℃; for 5h;

With water; at 4 - 20 ℃; for 2.5h;