Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Base Information

Chemical Name:Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate
CAS No.:135065-69-9
Molecular Formula:C10H19NO4
Molecular Weight:217.265
Hs Code.:2934999090
European Community (EC) Number:842-996-7
ChEMBL ID:CHEMBL4586987
DSSTox Substance ID:DTXSID90409523
Nikkaji Number:J2.377.408I
Mol file:135065-69-9.mol

Synonyms:N-Boc-2-hydroxymethylmorpholine;N-tert-butoxycarbonyl-2-hydroxymethylmorpholine

Suppliers and Price of Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Abosyn
tert-butyl2-(hydroxymethyl)morpholine-4-carboxylate 95-98%
1g
$ 680.00

Acrotein
N-Boc-2-hydroxymethylmorpholine 97%
1g
$ 83.42

AK Scientific
4-Boc-2-hydroxymethylmorpholine
1g
$ 55.00

Alichem
4-Boc-2-Hydroxymethylmorpholine
5g
$ 242.89

Alichem
4-Boc-2-Hydroxymethylmorpholine
25g
$ 686.80

Alichem
4-Boc-2-Hydroxymethylmorpholine
10g
$ 320.00

Ambeed
4-Boc-2-Hydroxymethylmorpholine 98%
25g
$ 388.00

Ambeed
4-Boc-2-Hydroxymethylmorpholine 98%
100g
$ 1090.00

Ambeed
4-Boc-2-Hydroxymethylmorpholine 98%
10g
$ 162.00

Ambeed
4-Boc-2-Hydroxymethylmorpholine 98%
5g
$ 84.00

Total 54 raw suppliers

Chemical Property of Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Chemical Property:

Vapor Pressure:2.53E-05mmHg at 25°C
Refractive Index:1.474
Boiling Point:320.7 °C at 760 mmHg
PKA:14.36±0.10(Predicted)
Flash Point:147.8 °C
PSA：59.00000
Density:1.118 g/cm³
LogP:0.55250
Storage Temp.:2-8°C
Solubility.:Dichloromethane, Ether, Ethyl Acetate,
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:217.13140809
Heavy Atom Count:15
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

tert-butyl2-(hydroxymethyl)morpholine-4-carboxylate 95-98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCOC(C1)CO
Uses Intermediate in the preparation of racemic analogs of Viloxazine.

Technology Process of Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

There total 14 articles about Tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 40987-24-4,943442-96-4
R,S-2-hydroxymethyl-4-benzylmorpholine

: 135065-69-9
tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Guidance literature:: palladium-carbon; In methanol;

Reference yield: 97.0%

: 189321-66-2
4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid

: 135065-69-9
tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Guidance literature:: 4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃; for 0.416667h;

With methanol; acetic acid; In tetrahydrofuran;