Technology Process of (+/-)-(1α,2β,3α,4α,5β)-2-azido-3,4-(dimethylmethylenedioxy)-5-<(phenylmethoxy)methyl>-1-cyclopentanol
There total 4 articles about (+/-)-(1α,2β,3α,4α,5β)-2-azido-3,4-(dimethylmethylenedioxy)-5-<(phenylmethoxy)methyl>-1-cyclopentanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
perchloric acid;
In
acetone;
for 1h;
Ambient temperature;
DOI:10.1021/jo00358a023
- Guidance literature:
-
Multi-step reaction with 4 steps
1: O2, thiourea, sodium acetate, Rose bengal / methanol / 9 h / -5 °C / Irradiation
2: 62 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Ambient temperature
3: 100 percent / sodium azide / dimethylformamide / 12 h / 110 °C
4: 92 percent / 75percent aq. HClO4 / acetone / 1 h / Ambient temperature
With
sodium azide; perchloric acid; oxygen; sodium acetate; rose bengal; thiourea; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jo00358a023
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 62 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Ambient temperature
2: 100 percent / sodium azide / dimethylformamide / 12 h / 110 °C
3: 92 percent / 75percent aq. HClO4 / acetone / 1 h / Ambient temperature
With
sodium azide; perchloric acid; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jo00358a023
