4-iodophenyl acrylate

Base Information

• Chemical Name: 4-iodophenyl acrylate
• CAS No.: 122340-98-1
• Molecular Formula: C₉H₇IO₂
• Molecular Weight: 274.058
• Mol file: 122340-98-1.mol

Synonyms:4-iodophenyl acrylate

Chemical Property of 4-iodophenyl acrylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-iodophenyl acrylate

There total 1 articles about 4-iodophenyl acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

p-Iodophenol (540-38-5) + acryloyl chloride (814-68-6,25189-84-8) → 4-iodophenyl acrylate (122340-98-1)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4.5h;

DOI:10.1002/asia.201300595

Reference yield:

α-acetyl-α-(3',4'-methylenedioxyphenyl)acetonitrile (24966-30-1) + 4-iodophenyl acrylate (122340-98-1) → C20H16INO5 + C20H16INO5

Guidance literature:

With (3R,4S,8R,9S)-9-{[tert-butyl(dimethyl)silyl]oxy}cinchonan-6'-ol; In chlorobenzene; at 20 ℃; for 60h; Reagent/catalyst; Overall yield = 94 %; enantioselective reaction; Schlenk technique;

DOI:10.1002/asia.201300595

Reference yield:

4-iodophenyl acrylate (122340-98-1) + C12H12BrNO3 (1334171-09-3) → C21H19BrINO5 + C21H19BrINO5 (1334171-12-8)

Guidance literature:

With epiCDT; In para-xylene; at 25 ℃; for 72h; optical yield given as %ee;

DOI:10.1002/anie.201103198

upstream raw materials:

p-Iodophenol

acryloyl chloride

Downstream raw materials:

C₂₁H₁₉BrINO₅