tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate
CAS No.:301221-57-8
Molecular Formula:C₁₂H₂₄N₂O₃
Molecular Weight:244.334
Hs Code.:
Mol file:301221-57-8.mol

Synonyms:tert-butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate?

Suppliers and Price of tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
1-Boc-4-(2-amino-1-hydroxyethyl)piperidine 97%
1g
$ 302.50

AK Scientific
1-Boc-4-(2-Amino-1-hydroxyethyl)piperidine
100mg
$ 128.00

AK Scientific
1-Boc-4-(2-Amino-1-hydroxyethyl)piperidine
1g
$ 518.00

Alichem
tert-Butyl4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
1g
$ 410.04

Alichem
tert-Butyl4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
5g
$ 1279.42

Alichem
tert-Butyl4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
250mg
$ 172.27

American Custom Chemicals Corporation
TERT-BUTYL-4-(2-AMINO-1-HYDROXYETHYL)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 497.15

Biosynth Carbosynth
tert-Butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
2 g
$ 603.00

Biosynth Carbosynth
tert-Butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
500 mg
$ 200.00

Biosynth Carbosynth
tert-Butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate
1 g
$ 347.00

Total 25 raw suppliers

Chemical Property of tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:383.2±12.0 °C(Predicted)
PKA:12.62±0.35(Predicted)
Density:1.103±0.06 g/cm3 (20 oC 760 Torr)
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-4-(2-amino-1-hydroxyethyl)piperidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate

There total 4 articles about tert-Butyl-(2-aMino-1-hydroxyethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 301221-56-7
tert-butyl 4-(1-hydroxy-2-nitroethyl)piperidine-1-carboxylate

: 301221-57-8
tert-butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate?

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 2585.81 Torr;

Reference yield:

: 913642-47-4
rac-tert-butyl 4-[cyano(hydroxy)methyl]piperidine-1-carboxylate

: 301221-57-8
tert-butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate?

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

Reference yield:

: 137076-22-3
tert butyl 4-formylpiperidine-1-carboxylate

: 301221-57-8
tert-butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate?

Guidance literature:: Multi-step reaction with 2 steps

1: DBU / tetrahydrofuran

2: H₂ / Pd/C / methanol

With hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2004.04.078