3-PYRIDINEACETIC ACID, 6-METHYL-,ETHYL ESTER

Base Information

• Chemical Name: 3-PYRIDINEACETIC ACID, 6-METHYL-,ETHYL ESTER
• CAS No.: 91843-27-5
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Mol file: 91843-27-5.mol

Synonyms:(6-Methylpyridin-3-yl)aceticacid ethyl ester

Chemical Property of 3-PYRIDINEACETIC ACID, 6-METHYL-,ETHYL ESTER

Chemical Property:

• PSA: 39.19000
• LogP: 1.49560

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-(6-methylpyridin-3-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PYRIDINEACETIC ACID, 6-METHYL-,ETHYL ESTER

There total 4 articles about 3-PYRIDINEACETIC ACID, 6-METHYL-,ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-(6-methylpyridin-3-yl)acetic acid (19733-96-1) + ethanol (64-17-5) → ethyl (6-methylpyridin-3-yl)acetate (91843-27-5)

Guidance literature:

With sulfuric acid; for 2h; Reflux;

DOI:10.1002/cmdc.201700783

Reference yield: 99.0%

→ ethyl (6-methylpyridin-3-yl)acetate (91843-27-5)

Guidance literature:

Reference yield:

ethyl 2-(6-methylpyridin-2-yl)acetate (5552-83-0) → ethyl (6-methylpyridin-3-yl)acetate (91843-27-5)

Guidance literature:

With m-chloroperoxybenzoic acid; In methanol; dichloromethane; chloroform;

upstream raw materials:

2-(6-methylpyridin-3-yl)acetic acid

ethanol

1-(6-methyl-pyridin-3-yl)-ethanone

ethyl 2-(6-methylpyridin-2-yl)acetate

Refernces

• 1、 -. "4-(PYRIDIN-3-YL)-2-(PYRIDIN-2-YL)-1,2-DIHYDRO-3H-PYRAZOL-3-ONE DERIVATIVES AS SPECIFIC HIF-PROLYL-4-HYDROXYLASE INHIBITORS FOR TREATING CARDIOVASCULAR AND HAEMATOLOGICAL DISEASES". Page/Page column 38. . Retrieved 2008/06/13.