1-Boc-2-methylpiperazine

Base Information

Chemical Name:1-Boc-2-methylpiperazine
CAS No.:120737-78-2
Molecular Formula:C10H20N2O2
Molecular Weight:200.281
Hs Code.:2933599090
European Community (EC) Number:676-407-8
DSSTox Substance ID:DTXSID40568013
Mol file:120737-78-2.mol

Synonyms:1-Boc-2-methylpiperazine;120737-78-2;tert-Butyl 2-methylpiperazine-1-carboxylate;n-1-boc-2-methylpiperazine;n-4-boc-3-methyl-piperazine;1-N-Boc-2-methylpiperazine;MFCD02179168;2-methyl-piperazine-1-carboxylic acid tert-butyl ester;2-methylpiperazine-1-carboxylic acid tert-butyl ester;1-Boc-2-methyl-piperazine;1-PIPERAZINECARBOXYLIC ACID, 2-METHYL-, 1,1-DIMETHYLETHYL ESTER;BOC-2-methylpiperazine;1-(tert-Butoxycarbonyl)-2-methylpiperazine;N1-Boc-2-methylpiperazine;SCHEMBL102293;DTXSID40568013;DATRVIMZZZVHMP-UHFFFAOYSA-N;AKOS005255320;AC-1786;CS-W008720;PB14271;PB32296;PS-3894;SB20878;t-butyl 2-methylpiperazine-1-carboxylate;SY005193;SY007943;SY018039;tert-Butyl2-methylpiperazine-1-carboxylate;A2531;AM20080152;EN300-82748;(+/-) tert-butyl 2-methylpiperazine-1-carboxylate;1,1-dimethylethyl 2-methyl-1-piperazinecarboxylate;W-200946;(1,1-dimethylethyl) 2-methyl-1-piperazinecarboxylate;Z1238542557;tert-butyl 2-methylpiperazine-1-carboxylate;N-1-Boc-2-methylpiperazine

Suppliers and Price of 1-Boc-2-methylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1-Boc-2-methylpiperazine
1g
$ 375.00

TRC
tert-Butyl2-Methylpiperazine-1-carboxylate
5mg
$ 55.00

SynQuest Laboratories
2-Methylpiperazine, N1-Boc protected
25 g
$ 164.00

SynQuest Laboratories
2-Methylpiperazine, N1-Boc protected
250 mg
$ 24.00

Oakwood
1-N-Boc-2-methylpiperazine 95%
5g
$ 40.00

Oakwood
1-N-Boc-2-methylpiperazine 95%
1g
$ 10.00

Medical Isotopes, Inc.
tert-Butyl2-methylpiperazine-1-carboxylate 95+%
1 g
$ 320.00

Medical Isotopes, Inc.
tert-Butyl2-methylpiperazine-1-carboxylate 95+%
5 g
$ 380.00

Matrix Scientific
N-1-Boc-2-methylpiperazine 95%
1g
$ 12.00

Matrix Scientific
N-1-Boc-2-methylpiperazine 95%
500mg
$ 10.00

Total 77 raw suppliers

Chemical Property of 1-Boc-2-methylpiperazine

Chemical Property:

Boiling Point:268.74 °C at 760 mmHg
PKA:8.49±0.40(Predicted)
Flash Point:116.33 °C
PSA：41.57000
Density:0.997 g/cm³
LogP:1.48190
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:200.152477885
Heavy Atom Count:14
Complexity:211

Purity/Quality:

99% ^*data from raw suppliers

1-Boc-2-methylpiperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNCCN1C(=O)OC(C)(C)C
Uses tert-Butyl 2-methylpiperazine-1-carboxylate is a useful reagent used in the synthesis of anthrafuran carboxamides with antitumor properties.

Technology Process of 1-Boc-2-methylpiperazine

There total 5 articles about 1-Boc-2-methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 128102-16-9
4-benzyl 1-tert-butyl 2-methylpiperazine-1,4-dicarboxylate

: 120737-78-2
tert-butyl 2-methylpiperazine-1-carboxylate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃;

Reference yield: 86.0%

: 120737-77-1
tert-butyl 2-methyl-4-benzyl-1-piperazinecarboxylate

: 120737-78-2
tert-butyl 2-methylpiperazine-1-carboxylate

Guidance literature:: With hydrogen; Pearlman's catalyst; In ethanol; at 20 ℃; under 1861.78 Torr;

Reference yield:

: 109-07-9
(RS)-2-methylpiperazine

: 120737-78-2
tert-butyl 2-methylpiperazine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 3 h / 0 - 20 °C

1.2: 0 - 20 °C

2.1: hydrogen / palladium 10% on activated carbon / methanol / 20 °C

With hydrogen; palladium 10% on activated carbon; In methanol; dichloromethane;