4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine

Base Information

Chemical Name:4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine
CAS No.:863550-42-9
Molecular Formula:C12H15 N3 O2
Molecular Weight:233.2664
Hs Code.:
DSSTox Substance ID:DTXSID10695729
Mol file:863550-42-9.mol

Synonyms:DTXSID10695729;4-(2,4-dimethoxyphenyl)-5-methylpyrazolidin-3-amine

Suppliers and Price of 4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(2,4-DIMETHOXYPHENYL)-5-METHYL-1H-PYRAZOL-3-AMINE 95.00%
5MG
$ 504.26

Total 5 raw suppliers

Chemical Property of 4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine

Chemical Property:

Boiling Point:401.1±45.0 °C(Predicted)
PKA:15.35±0.50(Predicted)
PSA：73.16000
Density:1.209±0.06 g/cm3(Predicted)
LogP:2.56570
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:237.147726857
Heavy Atom Count:17
Complexity:252

Purity/Quality:

99% ^*data from raw suppliers

4-(2,4-DIMETHOXYPHENYL)-5-METHYL-1H-PYRAZOL-3-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(NN1)N)C2=C(C=C(C=C2)OC)OC

Technology Process of 4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine

There total 2 articles about 4-(2,4-Dimethoxyphenyl)-5-methylpyrazolidin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 332179-40-5
2-(2,4-dimethoxyphenyl)-3-oxobutanenitrile

: 863550-42-9
4-(2,4-dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine

Guidance literature:: With hydrazine hydrochloride; In ethanol; Heating;
DOI:10.1016/j.bmcl.2004.05.019

Reference yield:

: 1891-11-8
(2,4-dimethoxyphenyl)acetonitrile

: 863550-42-9
4-(2,4-dimethoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran

1.2: tetrahydrofuran

2.1: NH₂NH₂*HCl / aq. ethanol / Heating

With hydrazine hydrochloride; sodium hydride; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2004.05.019