Chemical Property of 11-Mercaptoundecanoic acid
Chemical Property:
- Appearance/Colour:solid with an extremely unpleasant odour
- Vapor Pressure:0mmHg at 25°C
- Melting Point:46-50 °C(lit.)
- Refractive Index:1.483
- Boiling Point:352.209 °C at 760 mmHg
- PKA:4.78±0.10(Predicted)
- Flash Point:166.81 °C
- PSA：76.10000
- Density:0.998 g/cm3
- LogP:3.51170
- Storage Temp.:2-8°C
- XLogP3:4
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:10
- Exact Mass:218.13405111
- Heavy Atom Count:14
- Complexity:137
- Purity/Quality:
-
≥97% *data from raw suppliers
11-Mercaptoundecanoic acid
*data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C(CCCCCS)CCCCC(=O)O
-
Uses
MUA is used for the carboxylic acid functionalization of 1-dodecanethiol-protected gold nanoparticles (AuNPs) by Murray place-displacement reaction generally utilized in biomedical applications. It can also be used to modify the surface of platinum nanoparticles (PtNPs) by creating a ligand nano-assembly with a high surface coverage for use in surface-enhanced Raman spectroscopy (SERS). A single cell biochip platform can be developed utilizing a cell attachment technique with MUA forming a SAM that was attached to single cells. MUA may be used to prepare a tetrafluorophenyl-activated ester self-assembled monolayer to immobilize amine-modified oligonucleotides and DNA. It is also used to create 3D-assembled gold nanostructures for plasmonic biosensors. MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.
