4-Methoxy-2,6-dimethylbenzenesulfonyl chloride

Base Information

• Chemical Name: 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride
• CAS No.: 55661-08-0
• Molecular Formula: C9H11ClO3S
• Molecular Weight: 234.704
• Hs Code.: 2909309090
• European Community (EC) Number: 875-103-4
• DSSTox Substance ID: DTXSID10579530
• Nikkaji Number: J409.377A
• Wikidata: Q72489728
• Mol file: 55661-08-0.mol

Synonyms:55661-08-0;4-methoxy-2,6-dimethylbenzenesulfonyl chloride;4-methoxy-2,6-dimethylbenzene-1-sulfonyl chloride;4-methoxy-2,6-dimethyl-benzenesulfonyl chloride;MFCD00210327;Benzenesulfonyl chloride, 4-methoxy-2,6-dimethyl-;2,6-dimethyl-4-methoxyphenylsulfonyl chloride;2,6-Dimethyl-4-methoxybenzenesulphonyl chloride;4-Methoxy-2,6-dimethylbenzenesulfonylchloride;SCHEMBL152815;DTXSID10579530;FARJAHHRGCAAOY-UHFFFAOYSA-N;4-methoxy-2,6-dimethyl-benzensulfonyl;AKOS009208064;SB37650;AS-31302;SY008164;AM20040713;CS-0205628;EN300-36589;2,6-Dimethyl-4-methoxybenzenesulfonyl chloride;4-Methoxy-2,6-dimethyl-phenylsulfonyl chloride;4-methoxy-2,6-dimethyl benzenesulfonyl chloride;4-Methoxy-2,6-dimethylphenylsulfonic acid chloride;4-methoxy-2,6-dimethylbenzenesulfonic acid chloride;4-Methoxy-2 pound not6-dimethylbenzenesulfonyl Chloride

Chemical Property of 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• Boiling Point: 356.097 °C at 760 mmHg
• Flash Point: 169.162 °C
• PSA: 51.75000
• Density: 1.285 g/cm³
• LogP: 3.32030
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 234.0117431
• Heavy Atom Count: 14
• Complexity: 271

Purity/Quality:

97% ^*data from raw suppliers

4-Methoxy-2,6-dimethylbenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1S(=O)(=O)Cl)C)OC

Technology Process of 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride

There total 2 articles about 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3,5-dimethylmethoxybenzene (874-63-5) → 4-methoxy-2,6-dimethylbenzenesulfonyl chloride (55661-08-0)

Guidance literature:

With chlorosulfonic acid; In dichloromethane; at 0 - 20 ℃;

Reference yield: 36.0%

chlorosulfonic acid (7790-94-5) + 3,5-dimethylmethoxybenzene (874-63-5) → 4-methoxy-2,6-dimethylbenzenesulfonyl chloride (55661-08-0)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.166667h;

Reference yield: 100.0%

(2-hydroxyethyl)(methyl)amine (109-83-1) + 4-methoxy-2,6-dimethylbenzenesulfonyl chloride (55661-08-0) → N-(2-hydroxyethyl)-4-methoxy-2,6,N-trimethylbenzenesulphonamide (766558-31-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

upstream raw materials:

chlorosulfonic acid

3,5-dimethylmethoxybenzene

Downstream raw materials:

N^α-benzyloxycarbonyl-N^G-(4-methoxy-2,6-dimethylbenzenesulphonyl)arginine

(S)-methyl 4-(4-methoxy-2,6-dimethylphenylsulfonyl)-6,6-dimethylmorpholine-3-carboxylate

4-methoxy-2,6-dimethylbenzenethiol

N^G-Mds-Arg