5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde

Base Information

• Chemical Name: 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde
• CAS No.: 1439566-04-7
• Molecular Formula: C₆₃H₆₃N₃OS
• Molecular Weight: 910.279
• Mol file: 1439566-04-7.mol

Synonyms:5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde

Chemical Property of 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde

There total 1 articles about 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N,N-bis(4-(3,6-di-tert-butylcarbazol-9-yl)phenyl)-4-iodoaniline (1429922-05-3) + (5-formylthiophen-2-yl)boronic acid → 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde (1439566-04-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; water; for 24h; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201201479

Reference yield: 69.0%

rhodanine 3-acetic acid (5718-83-2) + 5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde (1439566-04-7) → (Z)-2-(5-{[5-(4-{bis-[4-(3,6-di-tert-butyl-9H-carbazol-9-yl)phenyl]amino}phenyl)thiophen-2-yl]methylidene}-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

Guidance literature:

With piperidine; In acetonitrile; for 2h; Reflux;

DOI:10.1016/j.mencom.2016.07.006

Reference yield: 58.0%

5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophene-2-carbaldehyde (1439566-04-7) + cyanoacetic acid (372-09-8) → (E)-3-[5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophen-2-yl]-2-cyanoacrylic acid (1439565-25-9)

Guidance literature:

With piperidine; In chloroform; for 18h; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201201479

upstream raw materials:

N,N-bis(4-(3,6-di-tert-butylcarbazol-9-yl)phenyl)-4-iodoaniline

Downstream raw materials:

(E)-3-[5-(4-{bis[4-(3,6-di-tert-butylcarbazol-9-yl)phenyl]amino}phenyl)thiophen-2-yl]-2-cyanoacrylic acid