1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol

Base Information

• Chemical Name: 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol
• CAS No.: 128459-28-9
• Molecular Formula: C₄₄H₅₀O₆
• Molecular Weight: 674.877
• Mol file: 128459-28-9.mol

Synonyms:1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol

Chemical Property of 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol

There total 6 articles about 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-myo-inositol (87-89-8) → 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol (128459-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) TMS-triflate, 4.) p-TsOH

2: sodium hydride / dimethylformamide

With trimethylsilyl trifluoromethanesulfonate; sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide;

DOI:10.1021/ja00042a011

Reference yield:

(1R)-(+)-camphor dimethyl acetal (109280-15-1) → 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol (128459-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) TMS-triflate, 4.) p-TsOH

2: sodium hydride / dimethylformamide

With trimethylsilyl trifluoromethanesulfonate; sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide;

DOI:10.1021/ja00042a011

Reference yield:

1D-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol (128459-27-8) + benzyl bromide (100-39-0) → 1D-1,4,5,6-O-tetrabenzyl-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol (128459-28-9)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1021/ja00042a011

upstream raw materials:

D-myo-inositol

(1R)-(+)-camphor dimethyl acetal

benzyl bromide

1D-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol

Downstream raw materials:

3,4,5,6-tetra-O-benzyl inositol

1,4,5,6-tetra-O-benzyl-myo-inositol

1D-2,3-O-(D-1',7',7'-trimethyl<2.2.1>bicyclohept-2'-ylidene)-myo-inositol