1-(4-Phenylphenyl)ethanamine

Base Information

• Chemical Name: 1-(4-Phenylphenyl)ethanamine
• CAS No.: 86217-82-5
• Molecular Formula: C14H15 N
• Molecular Weight: 197.28
• Hs Code.: 2921499090
• European Community (EC) Number: 818-281-0
• DSSTox Substance ID: DTXSID50378064
• Nikkaji Number: J1.120.544E
• ChEMBL ID: CHEMBL19081
• Mol file: 86217-82-5.mol

Synonyms:86217-82-5;1-(4-phenylphenyl)ethanamine;1-(1,1'-biphenyl-4-yl)ethanamine;1-Biphenyl-4-yl-ethylamine;1-(biphenyl-4-yl)ethanamine;4-(1-Aminoethyl)biphenyl;1-([1,1'-Biphenyl]-4-yl)ethanamine;CHEMBL19081;MFCD02667819;(1-biphenyl-4-ylethyl)amine;[1,1'-Biphenyl]-4-methanamine,a-methyl-;1-(4-Biphenylyl)ethylamine;SCHEMBL1168357;DTXSID50378064;1-(4-phenylphenyl)ethan-1-amine;alpha-Methylbiphenyl-4-methanamine;HMS1788N07;BDBM50023169;STK487809;AKOS000118560;AKOS016048868;1-(4-Biphenyl)ethylamine, AldrichCPR;AB91111;1-Biphenyl-4-yl-ethylamine, AldrichCPR;EN300-10022;N12276;Z56347114

Chemical Property of 1-(4-Phenylphenyl)ethanamine

Chemical Property:

• Vapor Pressure: 0.000201mmHg at 25°C
• Boiling Point: 327.5°C at 760 mmHg
• Flash Point: 156°C
• PSA: 26.02000
• Density: 1.027g/cm³
• LogP: 4.07360
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 197.120449483
• Heavy Atom Count: 15
• Complexity: 176

Purity/Quality:

98%Min ^*data from raw suppliers

4-(1-Aminoethyl)biphenyl ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,N,Xn
• Statements: 22-50
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=C(C=C1)C2=CC=CC=C2)N

Technology Process of 1-(4-Phenylphenyl)ethanamine

There total 12 articles about 1-(4-Phenylphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-acetylbiphenyl oxime (75408-89-8) → 1-(biphenyl-4-yl)ethanamine (86217-82-5)

Guidance literature:

With sodium hydrogensulfate monohydrate; molybdenum(V) chloride; sodium cyanoborohydride; In ethanol; for 2.5h; Reflux;

DOI:10.5012/bkcs.2011.32.9.3323

Reference yield: 91.0%

biphenyl-4-acetaldehyde (92-91-1) → 1-(biphenyl-4-yl)ethanamine (86217-82-5)

Guidance literature:

With 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate; In methanol; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/chem.201303541

Reference yield: 91.0%

→ 1-(biphenyl-4-yl)ethanamine (86217-82-5)

Guidance literature:

With ammonium formate; In methanol; at 80 ℃; for 0.166667h; Inert atmosphere;

With formic acid; C₂₉H₃₂ClIrNO; triethylamine; In methanol; at 80 ℃;

upstream raw materials:

biphenyl-4-acetaldehyde

ammonium formate

formamide

4-acetylbiphenyl oxime

Downstream raw materials:

2-Amino-1-biphenyl-4-yl-ethanone; hydrochloride

(+)-1-biphenyl-4-yl-ethylamine

(-)-1-biphenyl-4-yl-ethylamine

N-<1-(4-Biphenylyl)ethyl>-cis-4,5-diphenyl-2-oxazolidone-3-carboxamide