(S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline

Base Information

• Chemical Name: (S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline
• CAS No.: 811788-06-4
• Molecular Formula: C₂₆H₃₉N₃O₇
• Molecular Weight: 505.612
• Mol file: 811788-06-4.mol

Synonyms:(S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline

Chemical Property of (S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline

There total 1 articles about (S)-1-[N₂-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + Lisinopril (76547-98-3) + triethylamine (121-44-8) → (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline (811788-06-4)

Guidance literature:

In 1,4-dioxane; water; at 0 - 20 ℃;

Reference yield: 15.0%

(S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl(boc)]-L-proline (811788-06-4) + 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride (25952-53-8) + 1-bromo-3-propanol (627-18-9) → N-[(1S)-1-(3-bromopropoxycarbonyl)-3-phenylpropyl]-L-lysyl(boc)-L-proline 3-bromopropyl ester (811788-07-5)

Guidance literature:

With dmap; In dichloromethane; at 0 - 20 ℃; for 3h;

upstream raw materials:

di-tert-butyl dicarbonate

Lisinopril

triethylamine

Downstream raw materials:

N-[(1S)-1-(3-bromopropoxycarbonyl)-3-phenylpropyl]-L-lysyl(boc)-L-proline 3-bromopropyl ester