C₁₇H₂₉NO₅SSi

Base Information

• Chemical Name: C₁₇H₂₉NO₅SSi
• CAS No.: 1028432-16-7
• Molecular Formula: C₁₇H₂₉NO₅SSi
• Molecular Weight: 387.572
• Mol file: 1028432-16-7.mol

Synonyms:C₁₇H₂₉NO₅SSi

Chemical Property of C₁₇H₂₉NO₅SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₉NO₅SSi

There total 3 articles about C₁₇H₂₉NO₅SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl lactate (547-64-8,2155-30-8) + N-(tert-butyldimethylsilyloxy)-4-methylbenzenesulfonamide (1028432-04-3) → C17H29NO5SSi (1028432-16-7)

Guidance literature:

methyl lactate; N-(tert-butyldimethylsilyloxy)-4-methylbenzenesulfonamide; With triphenylphosphine; In tetrahydrofuran; toluene; for 0.166667h; Inert atmosphere; Cooling with ice;

With diethylazodicarboxylate; In tetrahydrofuran; toluene; at 0 - 10 ℃; Inert atmosphere;

DOI:10.15227/orgsyn.089.0480

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → C17H29NO5SSi (1028432-16-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydroxylamine hydrochloride / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

1.2: 10 °C

1.3: 10 °C

2.1: triphenylphosphine / toluene; tetrahydrofuran / 0.17 h / Inert atmosphere; Cooling with ice

2.2: 0 - 10 °C / Inert atmosphere

With hydroxylamine hydrochloride; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; 2.1: |Mitsunobu Displacement / 2.2: |Mitsunobu Displacement;

DOI:10.15227/orgsyn.089.0480

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → C17H29NO5SSi (1028432-16-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydroxylamine hydrochloride / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

1.2: 10 °C

1.3: 10 °C

2.1: triphenylphosphine / toluene; tetrahydrofuran / 0.17 h / Inert atmosphere; Cooling with ice

2.2: 0 - 10 °C / Inert atmosphere

With hydroxylamine hydrochloride; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; 2.1: |Mitsunobu Displacement / 2.2: |Mitsunobu Displacement;

DOI:10.15227/orgsyn.089.0480

upstream raw materials:

methyl lactate

N-(tert-butyldimethylsilyloxy)-4-methylbenzenesulfonamide

tert-butyldimethylsilyl chloride

p-toluenesulfonyl chloride

Downstream raw materials:

methyl pyruvate oxime