carbonic acid, 1-cyano-1-phenylethyl ethyl ester

Base Information

• Chemical Name: carbonic acid, 1-cyano-1-phenylethyl ethyl ester
• CAS No.: 1236289-45-4
• Molecular Formula: C₁₂H₁₃NO₃
• Molecular Weight: 219.24
• Mol file: 1236289-45-4.mol

Synonyms:carbonic acid, 1-cyano-1-phenylethyl ethyl ester

Chemical Property of carbonic acid, 1-cyano-1-phenylethyl ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of carbonic acid, 1-cyano-1-phenylethyl ethyl ester

There total 1 articles about carbonic acid, 1-cyano-1-phenylethyl ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

acetophenone (98-86-2) + ethyl cyanoformate (623-49-4) → carbonic acid, 1-cyano-1-phenylethyl ethyl ester (1236289-45-4)

Guidance literature:

With dmap; at 20 ℃; for 24h; Inert atmosphere; Neat (no solvent);

DOI:10.1016/j.tetlet.2010.04.123

Reference yield: 90.0%

carbonic acid, 1-cyano-1-phenylethyl ethyl ester (1236289-45-4) + methyl 3-oxo-3-phenylpropionate (614-27-7) → C20H18O3

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; C₃₃H₃₂FeN₃P; caesium carbonate; In toluene; at 60 ℃; for 24h; Reagent/catalyst; Solvent; enantioselective reaction; Inert atmosphere;

upstream raw materials:

acetophenone

ethyl cyanoformate