1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

Base Information

Chemical Name:1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide
CAS No.:279237-31-9
Molecular Formula:C₂₇H₄₀N₆O₄
Molecular Weight:512.652
Hs Code.:

Synonyms:1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

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Chemical Property of 1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

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Technology Process of 1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

There total 1 articles about 1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 173774-50-0
N-Boc-piperazine-2-amidoanhydride

: 61981-79-1
2-(2-methyl-benzimidazol-1-yl)-ethylamine

: 3173-53-3
Cyclohexyl isocyanate

: 279237-31-9
1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

Guidance literature:: N-Boc-piperazine-2-amidoanhydride; 2-(2-methyl-benzimidazol-1-yl)-ethylamine; In dichloromethane; at 20 ℃;

Cyclohexyl isocyanate; In dichloromethane; for 15h;

Reference yield:

: 279237-31-9
1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide

: 100-52-7
benzaldehyde

: 281197-77-1
N₁-cyclohexyl-N₂-[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]-4-(phenylethyl)-1,2(R)-piperazinedicarboxamide

Guidance literature:: 1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

benzaldehyde; With sodium tris(acetoxy)borohydride; In dichloromethane; acetic acid; at 20 ℃; for 48h;