(2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on

Base Information

• Chemical Name: (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on
• CAS No.: 109918-57-2
• Molecular Formula: C₁₈H₂₄N₂O₂
• Molecular Weight: 300.401
• Mol file: 109918-57-2.mol

Synonyms:(2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on

Chemical Property of (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on

There total 5 articles about (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dichloromethane (75-09-2) + (2R,5R)-1-benzoyl-2-(tert-butyl)-3,5-dimethyl-5-(3'-thiabutyl)imidazolidin-4-one (98262-63-6) → (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on (109918-57-2)

Guidance literature:

With sodium periodate; In methanol; 5,5-dimethyl-1,3-cyclohexadiene; water;

Reference yield:

(2S,5S)-1-benzoyl-2-(tert-butyl)-3-methyl-5-(3'-thiabutyl)imidazolidin-4-one (97443-89-5) → (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on (109918-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 35percent H₂O₂ / 1.) AcOH, room temperature, 4 h, 2.) xylol, 210 deg C, 2 h

2: 1.) LiN(i-Pr)2 / 1.) THF, -75 deg C, 30 min, 2.) THF, -75 deg C - 0 deg C, 2h

With dihydrogen peroxide; lithium diisopropyl amide;

DOI:10.1002/hlca.19860690611

Reference yield:

(2R,5R)-1-benzoyl-2-(tert-butyl)-3,5-dimethyl-5-(3'-thiabutyl)imidazolidin-4-one (98262-63-6) → (2S,5R)-1-Benzoyl-2-(tert-butyl)-3,5-dimethyl-5-vinylimidazolidin-4-on (109918-57-2)

Guidance literature:

With sodium periodate; Yield given. Multistep reaction; 1.) methanol, water, 4 h, room temperature, 2.) xylol, 210 deg C, 2 h;

DOI:10.1002/hlca.19860690611

upstream raw materials:

(2R,5R)-1-benzoyl-2-(tert-butyl)-3,5-dimethyl-5-(3'-thiabutyl)imidazolidin-4-one

(2S,5S)-1-benzoyl-2-(tert-butyl)-3-methyl-5-vinylimidazolidin-4-one

methyl iodide

(2S,5S)-1-benzoyl-2-(tert-butyl)-3-methyl-5-(3'-thiabutyl)imidazolidin-4-one

Downstream raw materials:

(R)-2-amino-2-methyl-3-butenoic acid

(R)-2-methylhomoserine