(3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane

Base Information

• Chemical Name: (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane
• CAS No.: 213833-70-6
• Molecular Formula: C₁₄H₂₆OSi
• Molecular Weight: 238.445
• Mol file: 213833-70-6.mol

Synonyms:(3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane

Chemical Property of (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane

There total 3 articles about (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl magnesium iodide (917-64-6) + chloro-trimethyl-silane (75-77-4) + (R)-Carvone (6485-40-1,2244-16-8) → (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane (213833-70-6)

Guidance literature:

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether;

DOI:10.1016/S0040-4039(98)01367-7

Reference yield:

methyl magnesium iodide (917-64-6) + chloro-trimethyl-silane (75-77-4) + (R)-Carvone (6485-40-1,2244-16-8) → (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane (213833-70-6) + ((3S,5R)-5-Isopropenyl-2,3-dimethyl-cyclohex-1-enyloxy)-trimethyl-silane

Guidance literature:

With copper(l) iodide; lithium chloride; In tetrahydrofuran; at 0 ℃; for 0.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/0022-328X(95)05699-P

Reference yield:

chloro-trimethyl-silane (75-77-4) + (R)-Carvone (6485-40-1,2244-16-8) → (3R,5R)-(5-isopropenyl-2,3-dimethylcyclohex-1-enyloxy)trimethylsilane (213833-70-6) + ((3S,5R)-5-Isopropenyl-2,3-dimethyl-cyclohex-1-enyloxy)-trimethyl-silane

Guidance literature:

In tetrahydrofuran; at -78 - 22 ℃; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/0022-328X(95)05699-P

upstream raw materials:

methyl magnesium iodide

chloro-trimethyl-silane

(R)-Carvone

Downstream raw materials:

(3S,4S,5R,2'S,3a'R,6a'S)-3-[3-([1,3]dioxolan-2-yl)propyl]-4-(hexahydrofuro[2,3-b]furan-2'-yl)-4,5-dimethylcyclohexanone

(4S,5R,2'S,3a'R,6a'S)-3-[3-([1,3]dioxolan-2-yl)propyl]-4-(hexahydrofuro[2,3-b]furan-2'-yl)-4,5-dimethylcyclohex-2-enone

Methanesulfonic acid (1R,2R,3R,5R)-2-(2S,3aR,6aS)-hexahydro-furo[2,3-b]furan-2-yl-5-isopropenyl-2,3-dimethyl-cyclohexyl ester

(3R,4S,5R,2'S,3a'R,6a'S)-4-(hexahydrofuro[2,3-b]furan-2'-yl)-4,5-dimethyl-3-(pent-4-enyl)cyclohexanone