BENZOIC-3,5-D2 ACID

Base Information

• Chemical Name: BENZOIC-3,5-D2 ACID
• CAS No.: 37960-84-2
• Molecular Formula: C7H4 D2 O2
• Molecular Weight: 124.133663556
• Mol file: 37960-84-2.mol

Synonyms:3,5-Dideuteriobenzoicacid

Chemical Property of BENZOIC-3,5-D2 ACID

Chemical Property:

• PSA: 37.30000
• LogP: 1.38480

Purity/Quality:

99% ^*data from raw suppliers

Benzoic-3,5-d2Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Benzoic-3,5-d2 Acid (CAS# 37960-84-2) is a useful isotopically labeled research compound.

Technology Process of BENZOIC-3,5-D2 ACID

There total 11 articles about BENZOIC-3,5-D2 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,5-dichlorobenzoic acid (51-36-5) → [3,5-D2]benzoic acid (37960-84-2)

Guidance literature:

With deuterated hypophosphorous acid; palladium 10% on activated carbon; sodium carbonate; In water-d2; at 50 ℃; regioselective reaction;

DOI:10.1002/jlcr.3277

Reference yield: 84.0%

carbon dioxide (124-38-9,18923-20-1) + 1-bromo-3,5-dideuteriobenzene (7291-07-8) → [3,5-D2]benzoic acid (37960-84-2)

Guidance literature:

With magnesium;

Reference yield:

3,5-dibromobenzoic acid (618-58-6) → [3,5-D2]benzoic acid (37960-84-2)

Guidance literature:

With deuteriated sodium hydroxide; copper aluminum; at 40 ℃; for 0.5h; Yield given;

upstream raw materials:

carbon dioxide

1-bromo-3,5-dideuteriobenzene

3,5-dibromoacetophenone

3,5-dibromobenzoic acid

Downstream raw materials:

3,5-dideuterio-1,4-dihydrobenzoic acid