TRI(2-FURYL)PHOSPHINE

Base Information

• Chemical Name: TRI(2-FURYL)PHOSPHINE
• CAS No.: 5518-52-5
• Molecular Formula: C12H9O3P
• Molecular Weight: 232.175
• Hs Code.: 29319090
• Mol file: 5518-52-5.mol

Synonyms:Phosphine,tri-2-furyl- (7CI,8CI);Tri-2-furanylphosphine;Tri-2-furylphosphine;Tris(2-furanyl)phosphine;Tris(2-furyl)phosphine;Tris(o-furyl)phosphine;Tri(2-furyl)phosphine;

Chemical Property of TRI(2-FURYL)PHOSPHINE

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 0.00456mmHg at 25°C
• Melting Point: 59-64 °C(lit.)
• Boiling Point: 286.4 °C at 760 mmHg
• Flash Point: 127 °C
• PSA: 53.01000
• LogP: 2.22380
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive.: air sensitive

Purity/Quality:

98% ^*data from raw suppliers

Tri(2-furyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: TRI(2-FURYL)PHOSPHINE is a phopshine ligand used in transition-metal mediated organic synthesis, in particular in wittig reactions to improved (Z) selectivity. suzuki reaction A phopshine ligand used in transition-metal mediated organic synthesis, in particular in wittig reactions to improved (Z) selectivity.

Technology Process of TRI(2-FURYL)PHOSPHINE

There total 7 articles about TRI(2-FURYL)PHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + tris(2-furyl)phosphane-borane(1:1) (1186392-97-1) → trifuran-2-yl-phosphane (5518-52-5) + triethyl borate (150-46-9)

Guidance literature:

Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2009.05.063

Reference yield: 90.0%

→ trifuran-2-yl-phosphane (5518-52-5)

Guidance literature:

Reference yield: 89.0%

tris(furan-2-yl)phosphine oxide (1021-20-1) → trifuran-2-yl-phosphane (5518-52-5)

Guidance literature:

tris(furan-2-yl)phosphine oxide; With trityl tetrakis(pentafluorophenyl)borate; In ⁽²⁾H₈-toluene; at 20 ℃; Glovebox; Inert atmosphere;

With phenylsilane; In ⁽²⁾H₈-toluene; at 80 ℃; for 1.5h; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.202100189

upstream raw materials:

furan

2-lithiofuran

Ag(tris(2-furyl)phosphine)3(ONO₂)

ethanol

Downstream raw materials:

1-[3-(2,4-Difluoro-benzyl)-phenyl]-ethanone

3-(2-fluorophenyl)-5-(2-methyl-2H-1,2,4-triazol-3-ylmethoxy)-6-(2,2-dimethylpropyl)-1,2,3-triazolo[4,5-b]pyridine

4-Methoxybenzyl (1S,5R,6S)6-((1R)-1-hydroxyethyl)-2-vinyl-1-methylcarbapen-2-em-3-carboxylate

2-amino-5-{2-[1-(4-chlorophenyl)cyclopentyl]vinyl}-6-methyl-4-pyrimidinylamine

Refernces

• 1、 Taylor, Nicholas P.,Gonzalez, Jorge A.,Nichol, Gary S.,García-Domínguez, Andrés,Leach, Andrew G.,Lloyd-Jones, Guy C.. "A Lewis Base Nucleofugality Parameter, NFB, and Its Application in an Analysis of MIDA-Boronate Hydrolysis Kinetics". supporting information. p. 721 - 729. Retrieved 2022/01/04.
• 2、 -. "PROCESS FOR PRODUCTION OF PHOSPHINE DERIVATIVE FROM PHOSPHINE OXIDE DERIVATIVE". Page/Page column 10. . Retrieved 2011/04/18.