2-Methoxy-3,5-dimethylbenzoic acid

Base Information

Chemical Name:2-Methoxy-3,5-dimethylbenzoic acid
CAS No.:21553-47-9
Molecular Formula:C₁₀H₁₂O₃
Molecular Weight:180.203
Hs Code.:
DSSTox Substance ID:DTXSID101297958
Nikkaji Number:J1.398.306B
Wikidata:Q107842458

Synonyms:2-methoxy-3,5-dimethylbenzoic acid;21553-47-9;Benzoic acid, 2-methoxy-3,5-dimethyl-;starbld0018702;SCHEMBL10920134;WEUQEKDZMFUQFT-UHFFFAOYSA-N;DTXSID101297958;MFCD14537327;AKOS005151551;CS-0196018;E90902

Suppliers and Price of 2-Methoxy-3,5-dimethylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Methoxy-3,5-dimethylbenzoic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:180.078644241
Heavy Atom Count:13
Complexity:191

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C(=O)O)OC)C

Technology Process of 2-Methoxy-3,5-dimethylbenzoic acid

There total 15 articles about 2-Methoxy-3,5-dimethylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.8%

: 124-38-9,18923-20-1
carbon dioxide

: 65492-45-7
1-bromo-2-methoxy-3,5-dimethylbenzene

: 21553-47-9
2-Methoxy-3,5-dimethylbenzoic acid

Guidance literature:: With n-butyllithium; In diethyl ether;
DOI:10.1002/ps.2780410210

Reference yield:

: 6738-23-4
2,4-dimethylanisole

: 21553-47-9
2-Methoxy-3,5-dimethylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 25.6 percent / Br₂; acetic acid / Fe / 5 h / 50 °C

2: 36.8 percent / n-butyl lithium / diethyl ether

With n-butyllithium; bromine; acetic acid; iron; In diethyl ether; 1: Bromination / 2: Carboxylation;
DOI:10.1002/ps.2780410210

Reference yield:

: 105-67-9
2,4-Xylenol

: 21553-47-9
2-Methoxy-3,5-dimethylbenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / NaH / dimethylformamide / 5 h / 20 °C

2: 25.6 percent / Br₂; acetic acid / Fe / 5 h / 50 °C

3: 36.8 percent / n-butyl lithium / diethyl ether

With n-butyllithium; bromine; sodium hydride; acetic acid; iron; In diethyl ether; N,N-dimethyl-formamide; 1: Methylation / 2: Bromination / 3: Carboxylation;
DOI:10.1002/ps.2780410210