α-(4-vinylphenyl)hexaethylene glycol

Base Information

• Chemical Name: α-(4-vinylphenyl)hexaethylene glycol
• CAS No.: 445434-22-0
• Molecular Formula: C₂₀H₃₂O₇
• Molecular Weight: 384.47
• Mol file: 445434-22-0.mol

Synonyms:α-(4-vinylphenyl)hexaethylene glycol

Chemical Property of α-(4-vinylphenyl)hexaethylene glycol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(4-vinylphenyl)hexaethylene glycol

There total 2 articles about α-(4-vinylphenyl)hexaethylene glycol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

p-acetoxystyrene (2628-16-2) + toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester (42749-28-0) → α-(4-vinylphenyl)hexaethylene glycol (445434-22-0)

Guidance literature:

p-acetoxystyrene; With potassium hydroxide; In ethanol; at 20 ℃; for 1h;

With sodium ethanolate; In ethanol; for 1h; Heating;

toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester; In ethanol; Further stages.; Heating;

DOI:10.1021/jo020071b

Reference yield:

pentaethylene glycol (2615-15-8) → α-(4-vinylphenyl)hexaethylene glycol (445434-22-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Et₃N; DMAP / CH₂Cl₂ / 0 - 20 °C

2.1: KOH / ethanol / 1 h / 20 °C

2.2: NaOEt / ethanol / 1 h / Heating

2.3: 54 percent / ethanol / Heating

With dmap; potassium hydroxide; triethylamine; In ethanol; dichloromethane;

DOI:10.1021/jo020071b

upstream raw materials:

p-acetoxystyrene

toluene-4-sulfonic acid 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethyl ester

pentaethylene glycol

Refernces