1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate

Base Information

• Chemical Name: 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate
• CAS No.: 951238-66-7
• Molecular Formula: C₇H₇O₃S*C₁₄H₁₃N₂O₂
• Molecular Weight: 412.466
• Mol file: 951238-66-7.mol

Synonyms:1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate

Chemical Property of 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate

There total 3 articles about 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl p-toluene sulfonate (80-48-8) + 2-(o-nitrostyryl)-pyridine (77340-84-2) → 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate (951238-66-7)

Guidance literature:

In acetonitrile; at 82 ℃; for 24h; Industrial scale;

DOI:10.1021/op5003402

Reference yield:

2-nitro-benzaldehyde (552-89-6) → 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate (951238-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride / 28 h / 140 °C / Industrial scale

2: acetonitrile / 24 h / 82 °C / Industrial scale

In acetic anhydride; acetonitrile;

DOI:10.1021/op5003402

Reference yield:

α-picoline (109-06-8) → 1-methyl-2-[(E)-2-(2-nitrophenyl)-ethenyl]-pyridinium 4-methylbenzenesulfonate (951238-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride / 28 h / 140 °C / Industrial scale

2: acetonitrile / 24 h / 82 °C / Industrial scale

In acetic anhydride; acetonitrile;

DOI:10.1021/op5003402

upstream raw materials:

methyl p-toluene sulfonate

2-(o-nitrostyryl)-pyridine

2-nitro-benzaldehyde

α-picoline

Downstream raw materials:

(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]benzenamine (1R,3S)-(+)-camphoric acid salt

(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine 4-methylbenzenesulfonate