(S)-(+)-3-Quinuclidinol

Base Information Edit

Chemical Name:(S)-(+)-3-Quinuclidinol
CAS No.:34583-34-1
Molecular Formula:C7H13NO
Molecular Weight:127.186
Hs Code.:29349990
European Community (EC) Number:681-383-7
UNII:2XEB6A770I
Nikkaji Number:J522.548E
Wikidata:Q27255758
Mol file:34583-34-1.mol

Synonyms:34583-34-1;(S)-Quinuclidin-3-ol;(S)-(+)-3-Quinuclidinol;(3s)-quinuclidin-3-ol;(S)-3-Quinuclidinol;(S)-3-Hydroxyquinuclidine;(3S)-1-azabicyclo[2.2.2]octan-3-ol;(S)-3-Quinuclidol;3-Quinuclidinol, (+)-;S-(+)-3-QUINUCLIDINOL;2XEB6A770I;UNII-2XEB6A770I;(+)-3-quinuclidinol;1-Azabicyclo(2.2.2)octan-3-ol, (3S)-;(S)-(+)-1-Azabicyclo(2.2.2)octan-3-ol;S-3-quinuclidinol;1-Azabicyclo[2.2.2]octan-3-ol, (3S)-;l-3-Quinuclidinol;(-)-3-Quinuclidinol;S-Quinuclidin-3-ol;(3S)-3-Quinuclidinol;3-(s)-hydroxy-quinuclidine;SCHEMBL74513;(S)-(-)-quinuclidin-3-ol;S-(+)-3-Hydroxy quinuclidine;(3S)-(+)-quinuclidin-3-ol;IVLICPVPXWEGCA-SSDOTTSWSA-N;CS-B0279;MFCD00211252;AKOS006343987;AKOS022172788;(S)-1-Azabicyclo[2.2.2]octan-3-ol;AC-26497;AC-26498;CS-13183;PD060384;(-)- (8CI);(3S)-3-hydroxy-1-azabicyclo[2.2.2]octane;(S)-(-)-1-Azabicyclo[2.2.2]octan-3-ol;A852179;W-202415;Q27255758;(3S)-1-Azabicyclo[2.2.2]octan-3-ol ((3S)-3-Quinuclidinol)

Suppliers and Price of (S)-(+)-3-Quinuclidinol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3S)-1-Azabicyclo[2.2.2]octan-3-ol
50mg
$ 70.00

Medical Isotopes, Inc.
(3S)-1-Azabicyclo[2.2.2]octan-3-ol
1 g
$ 290.00

Frontier Specialty Chemicals
(S)-(+)-3-Quinuclidinol 98%
5g
$ 320.00

Frontier Specialty Chemicals
(S)-(+)-3-Quinuclidinol 98%
1g
$ 213.00

Cayman Chemical
(S)-(+)-3-Quinuclidinol ≥95%
500μg
$ 55.00

Cayman Chemical
(S)-(+)-3-Quinuclidinol ≥95%
1g
$ 105.00

Cayman Chemical
(S)-(+)-3-Quinuclidinol ≥95%
5g
$ 330.00

Alichem
(S)-(+)-3-Quinuclidinol
25g
$ 692.01

Alichem
(S)-(+)-3-Quinuclidinol
5g
$ 228.34

AK Scientific
(S)-(+)-3-Quinuclidinol
1g
$ 241.00

Total 96 raw suppliers

Chemical Property of (S)-(+)-3-Quinuclidinol Edit

Chemical Property:

Vapor Pressure:0.0545mmHg at 25°C
Melting Point:215-217 °C
Refractive Index:1.549
Boiling Point:206.9 °C at 760 mmHg
PKA:14.75±0.20(Predicted)
Flash Point:97.7 °C
PSA：23.47000
Density:1.13 g/cm³
LogP:0.01080
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:127.099714038
Heavy Atom Count:9
Complexity:108

Purity/Quality:

99% ^*data from raw suppliers

(3S)-1-Azabicyclo[2.2.2]octan-3-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1C(C2)O
Isomeric SMILES:C1CN2CCC1[C@@H](C2)O

Technology Process of (S)-(+)-3-Quinuclidinol

There total 37 articles about (S)-(+)-3-Quinuclidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3731-38-2
3-Quinuclidinone

: 3684-26-2,25333-42-0,34583-34-1,1619-34-7
(S)-quinuclidin-3-ol

Guidance literature:: With RuCl[(S)-daipena][(S)-3,5-xylyl-BINAP]; potassium tert-butylate; hydrogen; In isopropyl alcohol; at 10 ℃; for 6h; under 22801.5 Torr; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ja202296w

Reference yield: 92.0%

: 1193-65-3
3-quinuclidinone hydrochloride

: 3684-26-2,25333-42-0,34583-34-1,1619-34-7
(S)-quinuclidin-3-ol

Guidance literature:: With D-glucose; In aq. phosphate buffer; at 30 ℃; for 48h; pH=8; Concentration; Temperature; pH-value; Time;
DOI:10.1016/j.molcatb.2012.11.013