(tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane

Base Information

• Chemical Name: (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane
• CAS No.: 1240380-55-5
• Molecular Formula: C₂₉H₃₆O₃Si
• Molecular Weight: 460.689
• Mol file: 1240380-55-5.mol

Synonyms:(tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane

Chemical Property of (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane

There total 3 articles about (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(3S)-5-[1-tert-butyl-1,1-diphenylsilyl]oxy-1-penten-3-ol (91376-46-4) + p-Methoxybenzyl bromide (2746-25-0) → (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane (1240380-55-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2010.05.064

Reference yield: 80.0%

(2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-3-(4-methoxy-benzyloxy)-pentane-1,2-diol (326471-52-7) → (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane (1240380-55-5)

Guidance literature:

With 1H-imidazole; iodine; 5,15,10,20-tetraphenylporphyrin; In toluene; at 60 ℃; for 0.25h;

DOI:10.1055/s-0030-1259056

Reference yield:

(3S)-5-[1-tert-butyl-1,1-diphenylsilyl]oxy-1-penten-3-ol (91376-46-4) + p-Methoxybenzyl bromide (2746-25-0) → (tert-butyl)({(3S)-3-[(4-methoxybenzyl)oxy]pent-4-en-1-yl}oxy)diphenylsilane (1240380-55-5) + (3S)-3-((methoxyphenyl)methyl)oxy-5-hydroxy-1-pentene (317855-28-0)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃;

DOI:10.1002/hlca.200900410

upstream raw materials:

(3S)-5-[1-tert-butyl-1,1-diphenylsilyl]oxy-1-penten-3-ol

p-Methoxybenzyl bromide

(2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-3-(4-methoxy-benzyloxy)-pentane-1,2-diol

Downstream raw materials:

(3S)-3-((methoxyphenyl)methyl)oxy-5-hydroxy-1-pentene