(R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Base Information

Chemical Name:(R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride
CAS No.:1332324-13-6
Molecular Formula:C₂₆H₂₃N₂O₄S*Cl
Molecular Weight:494.999
Hs Code.:

Synonyms:(R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Suppliers and Price of (R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

There total 2 articles about (R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 1332324-12-5
(R)-6-formyl-7-methyl-5-oxo-8-phenyl-2,3-dihydro-thiazolo[3,2-a]pyridine-3-carboxylic acid methyl ester

: 100-52-7
benzaldehyde

: 141-43-5
ethanolamine

: 1332324-13-6
(R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Guidance literature:: (R)-6-formyl-7-methyl-5-oxo-8-phenyl-2,3-dihydro-thiazolo[3,2-a]pyridine-3-carboxylic acid methyl ester; benzaldehyde; ethanolamine; In methanol; acetonitrile; at 20 ℃; for 24h;

With hydrogenchloride; In methanol; water; at 20 ℃; for 0.0833333h;
DOI:10.1021/ol202080x

Reference yield:

: 341027-49-4
(3R)-7-methyl-5-oxo-8-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid methyl ester

: 1332324-13-6
(R)-2,3-dihydro-8,10-diphenyl-7-(2-hydroxyethyl)-3-methoxycarbonyl-5-oxothiazolo[3,2-b][2,7]naphthyridinium chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride / acetonitrile / 0.17 h / 20 °C / Inert atmosphere

1.2: 2 h / Reflux; Inert atmosphere

2.1: air / methanol; acetonitrile / 24 h / 20 °C

2.2: 0.08 h / 20 °C

With oxalyl dichloride; In methanol; acetonitrile;
DOI:10.1021/ol202080x