Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester
• CAS No.: 625382-97-0
• Molecular Formula: C₁₁H₈F₆O₃S
• Molecular Weight: 334.239
• Mol file: 625382-97-0.mol

Synonyms:Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester

Chemical Property of Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester

There total 1 articles about Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 3-(trifluoromethyl)phenylacetone (21906-39-8) → Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester (625382-97-0)

Guidance literature:

3-(trifluoromethyl)phenylacetone; With potassium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

N,N-phenylbistrifluoromethane-sulfonimide; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

DOI:10.1021/ol035959g

Reference yield: 71.0%

benzamide (55-21-0,27208-38-4) + Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester (625382-97-0) → N-[1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl]-benzamide + N-[1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl]-benzamide

Guidance literature:

With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In 1,4-dioxane; at 20 ℃; for 8h;

DOI:10.1021/ol035959g

Reference yield:

acetamide (60-35-5) + Trifluoro-methanesulfonic acid (Z)-1-methyl-2-(3-trifluoromethyl-phenyl)-vinyl ester (625382-97-0) → (Z)-N-(1-(3-(trifluoromethyl)phenyl)prop-1-en-2-yl)acetamide + (E)-N-(1-(3-(trifluoromethyl)phenyl)prop-1-en-2-yl)acetamide

Guidance literature:

With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In 1,4-dioxane; at 20 ℃; for 20h; Further Variations:; Reagents; Catalysts; Solvents; Temperatures; times; Product distribution;

DOI:10.1021/ol035959g

upstream raw materials:

N,N-phenylbistrifluoromethane-sulfonimide

3-(trifluoromethyl)phenylacetone

Refernces