4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Base Information

Chemical Name:4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester
CAS No.:1073549-18-4
Molecular Formula:C₂₆H₃₀FN₃O₄
Molecular Weight:467.54
Hs Code.:

Synonyms:4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Suppliers and Price of 4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

There total 10 articles about 4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₆H₂₉FN₂O₄

: 1073549-18-4
4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Guidance literature:: With hydroxylamine hydrochloride; sodium hydrogencarbonate; In ethanol; at 40 ℃; for 24h;

Reference yield:

: 1073549-08-2
4'-[2-ethoxy-5-(hydroxyiminomethyl)-4-vinylimidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

: 1073549-18-4
4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Guidance literature:: With hydrogen; palladium; In ethanol; for 1h;

Reference yield:

: 55666-42-7
tert-butyl 2-bromobenzoate

: 1073549-18-4
4'-[2-ethoxy-4-ethyl-5-(hydroxyiminomethyl)imidazol-1-ylmethyl]-3'-fluorobiphenyl-2-carboxylic acid t-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / isopropyl alcohol; water / 46 h / 90 °C / Inert atmosphere

2: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / 7 h / 90 °C / Inert atmosphere

3: sodium hydroxide / tetrabutylammomium bromide / toluene; water / 27 °C

4: caesium carbonate / palladium diacetate; catacxium A / toluene; water / 16 h / 90 °C / Inert atmosphere

5: hydroxylamine hydrochloride; sodium hydrogencarbonate / ethanol / 24 h / 40 °C

With N-Bromosuccinimide; hydroxylamine hydrochloride; sodium hydrogencarbonate; sodium carbonate; caesium carbonate; sodium hydroxide; dibenzoyl peroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide; palladium diacetate; catacxium A; In tetrachloromethane; ethanol; water; isopropyl alcohol; toluene;