N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

Base Information

Chemical Name:N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide
CAS No.:1241916-05-1
Molecular Formula:C₂₀H₁₇FN₆O
Molecular Weight:376.393
Hs Code.:

Synonyms:N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

Suppliers and Price of N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

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Technology Process of N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

There total 10 articles about N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 1241914-92-0
(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine

: 109-94-4
formic acid ethyl ester

: 1241916-05-1
N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

Guidance literature:: With triethylamine; In ethanol; at 120 ℃; for 0.5h; Microwave irradiation;

Reference yield: 8.0%

: 1241914-92-0
(R,S)-2-(amino(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine

: 1241916-05-1
N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

Guidance literature:: With triethanolamine; acetic acid; In ethanol; formic acid ethyl ester;

Reference yield:

: 1241914-95-3
(R,S)-2-((benzyloxycarbonylamino)(4-fluorophenyl)methyl)-quinazolin-4-yl-2,4,6-triisopropylbenzenesulfonate

: 1241916-05-1
N-((4-fluorophenyl)(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)methyl)formamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; potassium iodide / palladium dihydroxide / 2,4-dichlorophenoxyacetic acid dimethylamine; methanol

2: triethanolamine; acetic acid / ethanol; formic acid ethyl ester

With potassium iodide; triethanolamine; acetic acid; palladium dihydroxide; In methanol; ethanol; 2,4-dichlorophenoxyacetic acid dimethylamine; formic acid ethyl ester;