(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Base Information

Chemical Name:(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde
CAS No.:112497-17-3
Molecular Formula:C₁₅H₂₀O₄
Molecular Weight:264.321
Hs Code.:

Synonyms:(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Suppliers and Price of (4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

There total 11 articles about (4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 112497-16-2
(4S,6S)-4-Benzyloxymethyl-6-[1,3]dithian-2-yl-2,2-dimethyl-[1,3]dioxane

: 112497-17-3
(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Guidance literature:: With ammonium cerium(IV) nitrate; In water; acetonitrile;
DOI:10.1016/S0040-4039(01)80992-8

Reference yield:

: 30379-55-6
benzyloxyacetic acid

: 112497-17-3
(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Guidance literature:: Multi-step reaction with 11 steps

2: 70 percent / DIBAL, ZnCl₂ / tetrahydrofuran / -78 °C

3: 95 percent / t-BuBr / CHCl₃ / Heating

4: 1) Et₃O(+)*BF₄(-), 2) aq. K₂CO₃ / 1) CH₂Cl₂

5: 87 percent / tetrahydrofuran / -30 °C

6: imidazole / dimethylformamide

7: MeI, CaCO₃ / acetonitrile; H₂O

8: 70 percent / tetrahydrofuran / -78 °C

9: HF / acetonitrile; H₂O

10: CSA / CH₂Cl₂

11: 75 percent / Ce(NH₄)2(NO₃)6 / acetonitrile; H₂O

With 1H-imidazole; ammonium cerium(IV) nitrate; t-butyl bromide; camphor-10-sulfonic acid; hydrogen fluoride; triethyloxonium fluoroborate; diisobutylaluminium hydride; potassium carbonate; calcium carbonate; zinc(II) chloride; methyl iodide; In tetrahydrofuran; dichloromethane; chloroform; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4039(01)80992-8

Reference yield:

: 2930-05-4,14618-80-5,89616-40-0,16495-13-9
(S)-benzyl glycidyl ether

: 112497-17-3
(4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde

Guidance literature:: Multi-step reaction with 7 steps

1: 87 percent / tetrahydrofuran / -30 °C

2: imidazole / dimethylformamide

3: MeI, CaCO₃ / acetonitrile; H₂O

4: 70 percent / tetrahydrofuran / -78 °C

5: HF / acetonitrile; H₂O

6: CSA / CH₂Cl₂

7: 75 percent / Ce(NH₄)2(NO₃)6 / acetonitrile; H₂O

With 1H-imidazole; ammonium cerium(IV) nitrate; camphor-10-sulfonic acid; hydrogen fluoride; calcium carbonate; methyl iodide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4039(01)80992-8