2-(Hydroxymethyl)isonicotinamide

Base Information

Chemical Name:2-(Hydroxymethyl)isonicotinamide
CAS No.:84589-39-9
Molecular Formula:C₇H₈N₂O₂
Molecular Weight:152.153
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20509989
Wikidata:Q82367978
Mol file:84589-39-9.mol

Synonyms:2-(hydroxymethyl)isonicotinamide;84589-39-9;2-(HYDROXYMETHYL)PYRIDINE-4-CARBOXAMIDE;4-Pyridinecarboxamide, 2-(hydroxymethyl)-;4-Pyridinecarboxamide,2-(hydroxymethyl)-(9CI);SCHEMBL8594535;DTXSID20509989;CS-0434811

Suppliers and Price of 2-(Hydroxymethyl)isonicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-(hydroxymethyl)-4-Pyridinecarboxamide 97.00%
1G
$ 1530.00

AccelPharmtech
2-(hydroxymethyl)-4-Pyridinecarboxamide 97.00%
5G
$ 1700.00

AccelPharmtech
2-(hydroxymethyl)-4-Pyridinecarboxamide 97.00%
25G
$ 3120.00

American Custom Chemicals Corporation
2-(HYDROXYMETHYL)-4-PYRIDINECARBOXAMIDE 95.00%
5MG
$ 496.39

Crysdot
2-(Hydroxymethyl)isonicotinamide 97%
1g
$ 653.00

Crysdot
2-(Hydroxymethyl)isonicotinamide 97%
5g
$ 1404.00

Crysdot
2-(Hydroxymethyl)isonicotinamide 97%
10g
$ 1935.00

Total 8 raw suppliers

Chemical Property of 2-(Hydroxymethyl)isonicotinamide

Chemical Property:

PSA：77.20000
LogP:0.55700
XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:152.058577502
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

2-(hydroxymethyl)-4-Pyridinecarboxamide 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C=C1C(=O)N)CO

Technology Process of 2-(Hydroxymethyl)isonicotinamide

There total 7 articles about 2-(Hydroxymethyl)isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 67-56-1
methanol

: 1453-82-3
isonicotinamide

: 84589-39-9
2-hydroxymethyl-4-pyridinecarboxamide

Guidance literature:: With sulfuric acid; Irradiation;
DOI:10.1246/bcsj.61.2837

Reference yield:

: 499-80-9
pyridine-2,4-dicarboxylic acid

: 84589-39-9
2-hydroxymethyl-4-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / 80 °C / Inert atmosphere

2: sodium tetrahydroborate; calcium chloride / ethanol / 80 °C / Inert atmosphere

3: ammonium hydroxide / ethanol / Inert atmosphere

With ammonium hydroxide; sodium tetrahydroborate; toluene-4-sulfonic acid; calcium chloride; In ethanol; 1: |Fischer-Speier Esterification;
DOI:10.1016/j.bmc.2015.03.063

Reference yield:

: 142074-49-5
2-(ethoxycarbonyl)isonicotinic acid

: 84589-39-9
2-hydroxymethyl-4-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate; calcium chloride / ethanol / 80 °C / Inert atmosphere

2: ammonium hydroxide / ethanol / Inert atmosphere

With ammonium hydroxide; sodium tetrahydroborate; calcium chloride; In ethanol;
DOI:10.1016/j.bmc.2015.03.063