p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Base Information

Chemical Name:p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside
CAS No.:1449491-91-1
Molecular Formula:C₂₀H₃₃N₃O₆Si
Molecular Weight:439.584
Hs Code.:

Synonyms:p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Suppliers and Price of p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Chemical Property:

Purity/Quality:: 95%-98% ^*data from raw suppliers

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Technology Process of p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

There total 5 articles about p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1449491-90-0
p-methoxyphenyl 2,3-anhydro-6-O-(tert-butyldimethylsilyl)-4-O-methyl-α-D-allopyranoside

: 1449491-91-1
p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

: 1449491-93-3
p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-2-deoxy-2-azido-α-D-altropyranoside

Guidance literature:: With sodium azide; ammonium chloride; In methanol; water; at 80 ℃; for 72h; Overall yield = 82 %;
DOI:10.1016/j.tet.2013.07.018

Reference yield:

: 197449-36-8
p-methoxyphenyl 2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

: 1449491-91-1
p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydrogencarbonate; dihydrogen peroxide / acetonitrile / 4 h / 20 °C

2: 1H-imidazole / dichloromethane / 4 h / 0 °C

3: silver(l) oxide / N,N-dimethyl-formamide / 23 h / 20 °C / Inert atmosphere

4: ammonium chloride; sodium azide / methanol; water / 72 h / 80 °C

With 1H-imidazole; sodium azide; dihydrogen peroxide; ammonium chloride; potassium hydrogencarbonate; silver(l) oxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2013.07.018

Reference yield:

: 157430-16-5
C₁₉H₃₀O₅Si

: 1449491-91-1
p-methoxyphenyl 6-O-(tert-butyldimethylsilyl)-4-O-methyl-3-deoxy-3-azido-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydrogencarbonate; urea hydrogen peroxide adduct / acetonitrile / 70.5 h / 40 °C

2: silver(l) oxide / N,N-dimethyl-formamide / 23 h / 20 °C / Inert atmosphere

3: ammonium chloride; sodium azide / methanol; water / 72 h / 80 °C

With sodium azide; urea hydrogen peroxide adduct; ammonium chloride; potassium hydrogencarbonate; silver(l) oxide; In methanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2013.07.018