5-Amino-2-morpholinobenzonitrile

Base Information

Chemical Name:5-Amino-2-morpholinobenzonitrile
CAS No.:78252-12-7
Molecular Formula:C₁₁H₁₃N₃O
Molecular Weight:203.244
Hs Code.:
DSSTox Substance ID:DTXSID40509784
Wikidata:Q82367644
Mol file:78252-12-7.mol

Synonyms:5-Amino-2-morpholinobenzonitrile;78252-12-7;5-amino-2-morpholin-4-ylbenzonitrile;5-amino-2-(morpholin-4-yl)benzonitrile;5-AMINO-2-(4-MORPHOLINYL)BENZONITRILE;Benzonitrile, 5-amino-2-(4-morpholinyl)-;SCHEMBL2445959;DTXSID40509784;MFCD11053918;AKOS005171435;5-Amino-2-morpholin-4-ylbenzonitrile;RS-0372;FT-0679042;A865066

Suppliers and Price of 5-Amino-2-morpholinobenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Amino-2-morpholinobenzonitrile
50mg
$ 45.00

Matrix Scientific
5-Amino-2-morpholin-4-ylbenzonitrile
1g
$ 462.00

Matrix Scientific
5-Amino-2-morpholin-4-ylbenzonitrile
500mg
$ 300.00

Crysdot
5-Amino-2-morpholinobenzonitrile 95+%
1g
$ 365.00

Chemenu
5-amino-2-morpholin-4-ylbenzonitrile 95%
1g
$ 430.00

ChemBridge Corporation
5-amino-2-(4-morpholinyl)benzonitrile 95%
250 mg
$ 84.00

Biosynth Carbosynth
5-Amino-2-morpholin-4-ylbenzonitrile
1 g
$ 255.00

Biosynth Carbosynth
5-Amino-2-morpholin-4-ylbenzonitrile
500 mg
$ 150.00

Biosynth Carbosynth
5-Amino-2-morpholin-4-ylbenzonitrile
250 mg
$ 85.00

Biosynth Carbosynth
5-Amino-2-morpholin-4-ylbenzonitrile
2 g
$ 434.00

Total 13 raw suppliers

Chemical Property of 5-Amino-2-morpholinobenzonitrile

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Storage Temp.:2-8°C
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:203.105862047
Heavy Atom Count:15
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-2-morpholinobenzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=C(C=C(C=C2)N)C#N

Technology Process of 5-Amino-2-morpholinobenzonitrile

There total 6 articles about 5-Amino-2-morpholinobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 78252-12-7
5-amino-2-morpholin-4-yl-benzonitrile

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 3h;

Reference yield: 51.6%

: 78252-11-6
2-Morpholin-4-yl-5-nitro-benzonitrile

: 78252-12-7
5-amino-2-morpholin-4-yl-benzonitrile

Guidance literature:: With tin(II) chloride dihdyrate; In ethanol; for 6h; Reflux;

Reference yield:

: 16588-15-1
2-chloro-5-nitro-benzamide

: 78252-12-7
5-amino-2-morpholin-4-yl-benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: benzenesulfonyl chloride / DMF (N,N-dimethyl-formamide); toluene / 3 h / 20 - 145 °C

2: ethanol / 1 h / Heating / reflux

3: iron; ammonium chloride / ethanol; water / 0.83 h / 65 °C / Heating / reflux

With iron; ammonium chloride; benzenesulfonyl chloride; In DMF (N,N-dimethyl-formamide); ethanol; water; toluene;