3-ethynylbenzophenone

Base Information

• Chemical Name: 3-ethynylbenzophenone
• CAS No.: 69355-34-6
• Molecular Formula: C₁₅H₁₀O
• Molecular Weight: 206.244
• Mol file: 69355-34-6.mol

Synonyms:3-ethynylbenzophenone

Chemical Property of 3-ethynylbenzophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-ethynylbenzophenone

There total 2 articles about 3-ethynylbenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

→ 3-ethynylbenzophenone (69355-34-6)

Guidance literature:

Reference yield:

3-(3-hydroxy-3-methyl-1-butynyl)benzophenone (286433-31-6) → 3-ethynylbenzophenone (69355-34-6)

Guidance literature:

DOI:10.1055/s-2008-1032069

Reference yield: 2.0%

carbon monoxide (201230-82-2) + 3-ethynylbenzophenone (69355-34-6) → ketoprofen (22071-15-4,22161-86-0) + 3-(m-benzoyl-phenyl)-propionic acid (41652-24-8)

Guidance literature:

With potassium hydroxide; polyethylene glycol (PEG-400); potassium cyanide; nickel cyanide; cobalt(II) chloride; In toluene; at 90 ℃; for 24h; under 760 Torr;

DOI:10.1016/S0040-4039(00)74325-5

upstream raw materials:

3-(3-hydroxy-3-methyl-1-butynyl)benzophenone

Downstream raw materials:

ketoprofen

3-(m-benzoyl-phenyl)-propionic acid

3-(1,1-difluoroethyl)benzophenone

Refernces

• 1、 Yamauchi, Yusuke,Fukuhara, Tsuyoshi,Hara, Shoji,Senboku, Hisanori. "Electrochemical carboxylation of α,α-difluorotoluene derivatives and its application to the synthesis of α-fluorinated nonsteroidal anti-inflammatory drugs". . p. 428 - 442. Retrieved 2008/09/16.