Chemical Property of 3-Acetyl-beta-boswellic acid
Chemical Property:
- Vapor Pressure:2.51E-14mmHg at 25°C
- Melting Point:157-161℃
- Refractive Index:1.543
- Boiling Point:566.8 °C at 760 mmHg
- PKA:4.32±0.70(Predicted)
- Flash Point:171.4 °C
- PSA：63.60000
- Density:1.09 g/cm3
- LogP:7.66030
- Storage Temp.:-20°C Freezer
- Solubility.:Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Very Sligh
- XLogP3:8.3
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:3
- Exact Mass:498.37091007
- Heavy Atom Count:36
- Complexity:985
- Purity/Quality:
-
99%, *data from raw suppliers
3-O-Acetyl-β-boswellic acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C
- Isomeric SMILES:C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C
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Uses
Boswellic acids are pentacyclic triterpenes first isolated from the resin of Boswellia plants. They have anti-inflammatory and anti-arthritic actions in mice. β-acetyl-Boswellic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) that shows selectivity for 5-LO over 12-LO or COX. When studied as a 1:1 mixture with α-acetyl-boswellic acid, it inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells.[Cayman Chemical]
