O-Ethyl-L-tyrosine

Base Information

• Chemical Name: O-Ethyl-L-tyrosine
• CAS No.: 32795-52-1
• Molecular Formula: C11H15 N O3
• Molecular Weight: 209.245
• Hs Code.: 2922509090
• UNII: F10H9YA9VI
• Mol file: 32795-52-1.mol

Synonyms:32795-52-1;O-Ethyl-L-tyrosine;(S)-2-Amino-3-(4-ethoxyphenyl)propanoic acid;Z-Tyr(Et)-OH;L-Tyrosine, O-ethyl-;(2S)-2-amino-3-(4-ethoxyphenyl)propanoic acid;4-Ethoxyphenylalanine;F10H9YA9VI;3-(p-Ethoxyphenyl)-L-alanine;NSC-44162;UNII-F10H9YA9VI;SCHEMBL158881;RMYPEYHEPIZYDJ-JTQLQIEISA-N;NSC 44162;AKOS012010903;AC-26597;AM808151;CS-0433812;F79000;A875513

Chemical Property of O-Ethyl-L-tyrosine

Chemical Property:

• Melting Point: 236 °C
• Boiling Point: 362.3±32.0 °C(Predicted)
• PKA: 2.24±0.10(Predicted)
• PSA: 72.55000
• Density: 1.175±0.06 g/cm3(Predicted)
• LogP: 1.74000
• Storage Temp.: 2-8°C
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 209.10519334
• Heavy Atom Count: 15
• Complexity: 200

Purity/Quality:

97% ^*data from raw suppliers

Z-Tyr(Et)-OH 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=C(C=C1)CC(C(=O)O)N
• Isomeric SMILES: CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)N

Technology Process of O-Ethyl-L-tyrosine

There total 7 articles about O-Ethyl-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

diethyl sulfate (64-67-5) + N-acetyl-L-tyrosine (537-55-3) → β-p-ethoxyphenyl-β-alanine (32795-52-1,3909-20-4,748068-32-8)

Guidance literature:

DOI:10.1248/cpb.30.4435

Reference yield:

(S)-3-(4-ethoxyphenyl)-2-(2,2,2-trifluoroacetamido)propionic acid methyl ester → β-p-ethoxyphenyl-β-alanine (32795-52-1,3909-20-4,748068-32-8)

Guidance literature:

With water; potassium carbonate; In methanol; at 20 ℃;

Reference yield:

N-tert-butoxycarbonyl-O-ethyl-L-tyrosine (76757-91-0,247088-44-4) → β-p-ethoxyphenyl-β-alanine (32795-52-1,3909-20-4,748068-32-8)

Guidance literature:

With p-toluenesulfonic acid monohydrate; In tetrahydrofuran;

upstream raw materials:

diethyl sulfate

N-acetyl-L-tyrosine

N-tert-butoxycarbonyl-O-ethyl-L-tyrosine

L-tyrosine

Downstream raw materials:

(αS)-α-[(4-ethoxyphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

Boc-Tyr(Et)-Arg-OMe_.CH₃COOH

C.<-Tyr(Et)-Arg->.CH3COOH

C_.(-Tyr(Et)-Har-).CH₃COOH